Results 1 to 10 of about 2,137 (155)
Linking Cortical Morphometry in Self-Limited Epilepsy With Centrotemporal Spikes to Cognition, Function, and Molecular Architecture. [PDF]
This study provides a novel framework modeling neurodevelopment in self‐limited epilepsy with centrotemporal spikes. We identify eight biologically interpretable brain structural deviation patterns, which are linked to clinical phenotypes and molecular profiles involving cognition and mitochondrial function. This integration elucidates multidimensional
Yang S +6 more
europepmc +2 more sources
CF Recommender System Based on Ontology and Nonnegative Matrix Factorization (NMF)
Recommender systems are a kind of data filtering that guides the user to interesting and valuable resources within an extensive dataset. by providing suggestions of products that are expected to match their preferences. However, due to data overloading, recommender systems struggle to handle large volumes of data reliably and accurately before offering
Sajida Mhammedi +3 more
openaire +2 more sources
The fusion of high-resolution multispectral image (HrMSI) and low-resolution hyperspectral image (LrHSI) has been acknowledged as a promising method for generating a high-resolution hyperspectral image (HrHSI), which is also termed to be an essential part for precise recognition and cataloguing of the underlying materials.
Abdolraheem Khader +2 more
openaire +2 more sources
Nonnegative matrix factorization (NMF), which is aimed at making all elements of the factorization nonnegative and achieving nonlinear dimensional reduction at the same time, is an effective method for solving recommendation system problems. However, in many real‐world applications, most models learn recommendation models under the supervised learning ...
Ronghua Zhang +5 more
openaire +1 more source
Adaptive computation of the Symmetric Nonnegative Matrix Factorization (SymNMF)
Nonnegative Matrix Factorization (NMF), first proposed in 1994 for data analysis, has received successively much attention in a great variety of contexts such as data mining, text clustering, computer vision, bioinformatics, etc. In this paper the case of a symmetric matrix is considered and the symmetric nonnegative matrix factorization (SymNMF) is ...
P. Favati +3 more
openaire +3 more sources
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai +15 more
wiley +1 more source
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi +23 more
wiley +1 more source
ABSTRACT Widespread digital adoption has challenged our understanding of how these tools reshape collaboration, trust and sustainability outcomes across different institutional and network contexts. As networks now pursue resilience and sustainable development in parallel, we map emerging research directions and identify how collaboration and ...
Ari Carisza Graha Prasetia +1 more
wiley +1 more source
Features the major cell type compositions among colon and liver metastasis. (A) The study design for single‐cell data analysis. (B) The annotated major cell types. Each type was labeled with a special color. (C) Dot plot of canonical marker genes for major cell types. (D) Bar plot of the percentage for each cell type in individuals. (E) Bar plot of the
Zhixun Zhao +10 more
wiley +1 more source
In this work, we develop submicron‐resolution mapping of intracellular lipid elements (SMILE) as an extraction‐free vibrational spectroscopic imaging platform based on hyperspectral stimulated Raman scattering microscopy with a spectral analysis pipeline for pixel‐resolved lipid profiling.
Yihui Zhou +10 more
wiley +1 more source

