Results 101 to 110 of about 3,756 (234)

Testicular Microbiome: May Influence Testicular Architecture and Spermatogenesis, and Predict Results of Microsurgical Testicular Sperm Extraction

open access: yesAndrologia, Volume 2025, Issue 1, 2025.
Purpose To investigate the bacterial microbiome pattern of testicular tissue and its potential role in male infertility and in predicting micro‐TESE results. Methods A total of 180 infertile men, including nonobstructive azoospermia (NOA) cases, referred to as the study group, and men with previous unsuccessful IVF treatments and/or a sperm DNA ...
Ayse Altun Akpınar   +7 more
wiley   +1 more source

Pengaruh Madu Terhadap Gambaran Mikroskopis Testis Pada Tikus Wistar Yang Diinduksi Monosodium Glutamat [PDF]

open access: yes, 2015
Background: Monosodium glutamate (MSG) is a food seasoning that is often consumed excessively although it is harmful to the body, including on testis. The harmful effect of MSG on testis must be highlighted because it can leaf to infertility. Honey as an
Amarwati, S. (Siti)   +2 more
core   +1 more source

Predictors of sperm retrieval with micro TESE, A narrative review article [PDF]

open access: yes, 2020
Introduction: Regarding the financial and psychological effects of micro-TESE on patients with NOA, it is important to determine the parameters by which the sperm retrieval with micro-TESE can be predicted.
Abedi, Amir Reza   +3 more
core   +2 more sources

Comparison of Pregnancy Rate and Live Birth Rate of Intracytoplasmic Sperm Injection Cycles Using Fresh Versus Frozen–Thawed Testicular Sperm

open access: yesObstetrics and Gynecology International, Volume 2025, Issue 1, 2025.
Objectives The primary objective of the study is to compare the rate of pregnancy and live birth rate in infertile couples with nonobstructive azoospermia (NOA) treated with either fresh or frozen sperms in intracytoplasmic sperm injection (ICSI) cycles.
Zeyad Mohammed Abualiat   +7 more
wiley   +1 more source

CITED2 Binding to EP300 Regulates Human Spermatogonial Stem Cell Proliferation and Survival Through HSPA6

open access: yesStem Cells International, Volume 2025, Issue 1, 2025.
Spermatogonial stem cells (SSCs) are essential for the initiation and continuation of spermatogenesis, a process fundamental to male fertility. Despite extensive studies on mouse SSCs, the mechanisms governing self‐renewal and differentiation in human SSCs remain to be elucidated.
Yongzhe Chen   +8 more
wiley   +1 more source

Prognostic factors for sperm retrieval in non-obstructive azoospermia [PDF]

open access: yes, 2013
Testicular sperm retrieval techniques associated with intracytoplasmic sperm injection have changed the field of male infertility treatment and given many azoospermic men the chance to become biological fathers.
Glina, Sidney, Vieira, Marcelo
core   +4 more sources

Varicocelectomy in men with nonobstructive azoospermia: Is it beneficial?

open access: yesInternational Journal of Surgery, 2009
To investigate the effect of open lymph sparing high ligation varicocelectomy in nonobstructive azoospermic men with palpable varicocele and determine predictive parameters of outcome.After a standard diagnostic evaluation, a total number of 83 men with nonobstructive azoospermia (54 men with complete azoospermia and 29 with virtual azoospermia) and ...
Youssef, Tamer   +4 more
openaire   +2 more sources

HSF5 Deficiency Causes Male Infertility Involving Spermatogenic Arrest at Meiotic Prophase I in Humans and Mice

open access: yesAdvanced Science, Volume 11, Issue 33, September 4, 2024.
The findings identify HSF5 as a novel genetic cause for human male infertility associated with meiotic arrest. Moreover, the molecular mechanism of HSF5 is first unambiguously elucidated as a transcriptional regulator orchestrating the transcriptome to ensure meiotic progression in humans and mice.
Mohan Liu   +21 more
wiley   +1 more source

Loss‐of‐function variant in TDRD6 cause male infertility with severe oligo‐astheno‐teratozoospermia in human and mice

open access: yesJournal of Cellular and Molecular Medicine, Volume 28, Issue 18, September 2024.
Abstract Oligo‐astheno‐teratozoospermia (OAT) is a common cause of male infertility, but the genetic basis of most OAT cases is still unknown. Here, one homozygous loss‐of‐function (LOF) variant in TDRD6, c.G1825T/p.Gly609X, was identified in an infertile patient with severe OAT by whole‐exome sequencing (WES) and Sanger confirmation.
Xinying Bi   +6 more
wiley   +1 more source

CCDC157 is essential for sperm differentiation and shows oligoasthenoteratozoospermia‐related mutations in men

open access: yesJournal of Cellular and Molecular Medicine, Volume 28, Issue 7, April 2024.
Abstract Oligoasthenoteratospermia (OAT), characterized by abnormally low sperm count, poor sperm motility, and abnormally high number of deformed spermatozoa, is an important cause of male infertility. Its genetic basis in many affected individuals remains unknown. Here, we found that CCDC157 variants are associated with OAT.
Huimei Zheng   +13 more
wiley   +1 more source

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