Results 81 to 90 of about 9,757 (189)

Pathogenic Variants in PET Complex Encoding Genes TDRD12 and EXD1 Impair piRNA Biogenesis and Cause Male Infertility

Human Mutation, Volume 2026, Issue 1, 2026.
Background Nonobstructive azoospermia (NOA), the most severe form of male infertility, has approximately 30% of its cases attributed to genetic factors. However, current genetic research only explains a small fraction of NOA cases. Methods Here, 156 infertile Chinese patients diagnosed with idiopathic male infertility were recruited.
Beibei Zhang, Ao Ma, Hongyi Wang, Chong Xie, Shengwei Ke, Ziqi Yu, Haoran Xu, Zhipeng Xu, Zhiran Li, Xun Wang, Lv Yao, Fuxing Zhang, Lingying Jiang, Xiaozhi Zhao, Fei Sun, Baisakhi Banerjee   +15 more
wiley   +1 more source

ICSI treatment of severe male infertility can achieve prospective embryo quality compared with IVF of fertile donor sperm on sibling oocytes

Asian Journal of Andrology, 2015
Azoospermia, cryptozoospermia and necrospermia can markedly decrease the ability of males to achieve pregnancy in fertile females. However, patients with these severe conditions still have the option to be treated by intracytoplasmic sperm injection ...
Ju-Fen Zheng, Xiao-Bao Chen, Lei-Wen Zhao, Min-Zhi Gao, Jie Peng, Xian-Qin Qu, Hui-Juan Shi, Xing-Liang Jin   +7 more
doaj   +1 more source

An artificial neural network for predicting the presence of spermatozoa in the testes of men with nonobstructive azoospermia

, 2004
Purpose: We developed an artificial neural network (ANN) for predicting spermatozoa prior to testicular biopsy in men with nonobstructive azoospermia.
Samli, MM, Dogan, I
core   +1 more source

Studying nonobstructive azoospermia in cystinosis: histologic examination of testes and epididymis and sperm analysis in a Ctns⁻/⁻ mouse model [PDF]

, 2012
OBJECTIVE: To study the pathogenesis of male infertility in cystinosis due to nonobstructive azoospermia, using a Ctns(-/-) mouse model. DESIGN: Observational case-control study. SETTING: Academic research laboratory.
Courtoy, Pierre J, Pastore, Anna, van Pelt, Ans M. M., Goossens, Ellen, Chevronnay, Heloise P. Gaide, van Pelt, Ans M M, Courtoy, Pierre J., Gaide Chevronnay, Héloïse P, Levtchenko, Elena N, Devuyst, Olivier, Antignac, Corinne, Besouw, Martine T. P., Besouw, Martine T P, Levtchenko, Elena N., Gaide Chevronnay, Héloïse P., Martine T P Besouw   +15 more
core   +1 more source

Somatic mutational analysis of DAX1 in testes from men with idiopathic azoospermia

, 2005
Mutations in the orphan nuclear receptor DAX1 (NR0B1) cause X-linked adrenal hypoplasia congenital (AHC), a disorder characterized by primary adrenal failure, hypogonadotropic hypogonadism. and azoospermia.
A. Spada, G. M. Colpi, G. Mantovani, M. Mancini, P. Beck-Peccoz, L. Persani, G. Gazzano   +6 more
core   +1 more source

Sperm cryopreservation protocol for micro-TESE-retrieved sperm

Asian Journal of Andrology
Azoospermia is characterized by the absence of sperm in the ejaculate and is categorized into obstructive azoospermia (OA) and nonobstructive azoospermia (NOA).
Vijay Mangoli, Evangelini Evgeni, Christine Wyns   +2 more
doaj   +1 more source

Large needle percutaneous aspiration biopsy of the testicle in men with nonobstructive azoospermia: technical performance

, 2006
The aim of this study was to relate retrospectively in 215 percutaneous large needle aspiration biopsy (LNAB) of the testicles the number of seminiferous tubules (ST) per testicular biopsy, from differently sized testicles, to the size of the needle used
TOLDIN MR, NARDINI V, TODESCHINI G, ROSSI G., FABRIS FG, NICOLINI, ANDREA, CARPI, ANGELO, Todeschini Giuseppe, Nardini Vincenzo, Nicolini Andrea, Rossi Giuseppe, Rosaria Maria, Carpi Angelo, Toldin Parisen, Giuseppe Fabrizio, Fabris Menchini   +15 more
core   +1 more source

Isotretinoin for the treatment of nonobstructive azoospermia

Asian Journal of Andrology, 2021
John K Amory, Charles H Muller, Thomas J Walsh   +2 more
openaire   +3 more sources

A differential cytokine expression profile before and after rFSH treatment in Sertoli cell cultures of men with nonobstructive azoospermia

, 2016
To evaluate the effects of follicle-stimulating hormone (FSH) treatment on cytokine gene expression in cultured Sertoli cells from men with nonobstructive azoospermia, a total of 15 azoospermic men diagnosed as obstructive azoospermia (OA) (n = 5) and ...
S. Heidargholizadeh, Y. Yukselten, Aydos, S. E., S. E. Aydos, Aydos, K., Heidargholizadeh, S., Sunguroglu, A., S. Ozkavukcu, Yukselten, Y., Ozkavukcu, S.; id_orcid, A. Sunguroglu, K. Aydos, Ozkavukcu, S.   +12 more
core   +1 more source

Association between JMJD1A Expression and Sperm Retrieval in Non-Obstructive Azoospermic Patients

Cell Journal, 2017
Identification of molecular markers which can predict the outcome of sperm retrieval non-invasively in patients with non-obstructive azoospermia (NOA) are valuable in clinical andrology.
Zahra Eelaminejad, Raha Favaedi, Tahereh Modarresi, Marjan Sabbaghian, Mohammad Ali Sadighi Gilani, Maryam Shahhoseini   +5 more
doaj   +1 more source