Results 81 to 90 of about 3,756 (234)

Emerging trends in the management of non‐obstructive azoospermia

open access: yesUroPrecision, Volume 3, Issue 2, Page 88-97, June 2025.
Abstract Ten percent of infertile males have azoospermia, classified into obstructive and nonobstructive types, which require specific medical or surgical treatments. In nonobstructive azoospermia, advancements in microsurgery allow for effective sperm retrieval in about half of cases.
Mina Saad   +4 more
wiley   +1 more source

STAG3 is a strong candidate gene for male infertility [PDF]

open access: yes, 2014
Oligo- and azoospermia are severe forms of male infertility. However, known genetic factors account only for a small fraction of the cases. Recently, whole-exome sequencing in a large consanguineous family with inherited premature ovarian failure (POF ...
Barbero, José Luis   +8 more
core   +3 more sources

Artificial intelligence and varicocelectomy: A new horizon for patient management? A narrative review

open access: yesUroPrecision, Volume 3, Issue 2, Page 61-70, June 2025.
Abstract Varicocele is a common entity found in 15% of men and is the most common reversible cause of male factor infertility. Guidelines have been developed to guide urologists in deciding which patients would benefit from varicocelectomy. Yet studies published over the last decade showed the emergence of predictors of success of varicocelectomy using
Oussama G. Nasrallah   +2 more
wiley   +1 more source

Azoospermia: a Genomic Review [PDF]

open access: yes, 2017
Azoospermia or the absence of sperm in semen is one of the sperm disorders that results in male infertility. There are two types of azoospermia, the first one isazoospermia caused by obstruction of the vas deferens (obstructive azoospermia) and the ...
Larasati, M. D. (Manggiasih)   +1 more
core  

Testicular fine needle aspirations cause histological injuryand immunological response in mouse testis [PDF]

open access: yes, 2008
The purpose of this study was to define the histopathological change and immunological response occurring as a result of testicular fine needle aspirations (TEFNAs) in C3H/HeN mice.
Tsuboi, Hiromu
core   +1 more source

Sperm retrieval outcomes of contralateral testis in men with nonobstructive azoospermia and unsuccessful unilateral microdissection testicular sperm extraction [PDF]

open access: bronze, 2023
Zhe Zhang   +9 more
openalex   +1 more source

MicroRNAs in seminal plasma are able to discern infertile men at increased risk of developing testicular cancer

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1188-1202, April 2025.
Male infertility is a known risk factor for the development of testicular cancer. In this paper, we analyzed the expression profile of a microRNA panel by real‐time PCR and validated the results by digital PCR. Experimental and bioinformatics analyses allowed us to identify possible biomarkers able to discern men with a higher risk of developing ...
Carmen Ferrara   +14 more
wiley   +1 more source

Genetic Variation in the Testis-Specific GSG3/CAPZA3 Gene Encoding for the Actin Regulatory Protein in Infertile Males [PDF]

open access: yes, 2014
アクチンキャッピング蛋白質 GSG3/CAPZA3 は、受精可能な精子の形態形成に重要な役割を担っている。GSG3/CAPZA3 遺伝子は、イントロンレス遺伝子として哺乳類に保存され、マウスにおいてミッセンス変異が精子の減少と形態異常を誘導し、雄性不妊症の原因となることが知られている。日本人において男性不妊症と GSG3/CAPZA3 遺伝子多型の関係を調べるため、261人の男性不妊症患者と139人の妊孕性が確認された男性ボランティアの遺伝子多型を調べた。その結果 ...
Akira TSUJIMURA   +7 more
core   +1 more source

Genetic Landscape of Nonobstructive Azoospermia and New Perspectives for the Clinic [PDF]

open access: yes, 2020
We thank Alejandro Fernández Sevilla for his valuable help in the development of Figure 2 of this review. The authors were funded by the Spanish Ministry of Economy and Competitiveness through the Spanish National Plan for Scientific and Technical ...
Carmona López, Francisco David   +3 more
core   +2 more sources

Integrating artificial intelligence in surgical sperm retrieval techniques: A narrative review

open access: yesUroPrecision, Volume 3, Issue 1, Page 17-26, March 2025.
Abstract Nonobstructive azoospermia (NOA) is a serious form of male infertility with therapeutic options limited to trials of endocrine manipulations and repertoire of surgical interventions, also known as surgical sperm retrieval (SSR) procedures. Despite its invasive nature, SSR remains crucial in the management of NOA, offering infertile males the ...
Hussein Kandil
wiley   +1 more source

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