Results 131 to 140 of about 724,098 (319)
Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1
Advanced Science, EarlyView.Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency +19 more
wiley +1 more source
Local Polynomial Fitting and Spatial Price Relationships: Price Transmission in the EU Markets for Pigmeat [PDF]
We apply nonparametric methods to assess price transmission processes within the EU pig markets. We compare results derived from nonparametric regressions with those obtained using alternative nonlinear threshold models.
Gil, Jose Maria +2 more
core +1 more source
Nonparametric Survival Analysis
Statistical Science, 2004 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis
Advanced Science, EarlyView.ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai +15 more
wiley +1 more source
Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy
Advanced Science, EarlyView.Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih +12 more
wiley +1 more source
Nonparametric statistical testing of EEG- and MEG-data.
Journal of Neuroscience Methods, 2007 E. Maris, R. Oostenveld
semanticscholar +1 more source
Nonparametric Bayesian Regression
The Annals of Statistics, 1986 The paper addresses itself to Bayesian estimation of the function \[ F(x_ 1,x_ 2)=m+a(x_ 1)+b(x_ 2)+c(x_ 1,x_ 2) \] in the model \(y_ i=F(x_{1i},x_{2i})+e_ i\). A prior for F is constructed by putting independent priors on m,a,b, and c. They are normal distribution and Brownian motion.
openaire +3 more sources
Advanced Science, EarlyView.This study integrates multi‐omics to reveal the critical role of UBE2T in driving malignancy and stromal co‐evolution in PDAC. UBE2T potentiates glycolysis by regulating p53 degradation via a positive feedback loop, thereby promoting histone H3 lysine 18 lactylation in CAFs and stromal deposition. The UBE2T inhibitor PGG represents a potential strategy
Yong Ma +16 more
wiley +1 more source
Adaptive Nonparametric Clustering
, 2017 This paper presents a new approach to non-parametric cluster analysis called Adaptive Weights Clustering (AWC). The idea is to identify the clustering structure by checking at different points and for different scales on departure from local homogeneity.
Adamyan, Larisa +2 more
core