AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song +6 more
wiley +1 more source
Parametric and nonparametric propensity score weighting analysis with subgroup covariate balance. [PDF]
Li Y, Kuo YF, Li L.
europepmc +1 more source
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed +15 more
wiley +1 more source
This paper introduces a resource‐aware Contrastive Scattering Meta‐Learning (CSML) framework for acoustic anomaly detection. By leveraging training‐free wavelet scattering and metric‐based meta‐learning, the model achieves competitive performance with only 50 K learnable parameters—a 98% reduction compared to state‐of‐the‐art frameworks—enabling ...
Rami Zewail, Bassem Mokhtar
wiley +1 more source
Brassinosteroids control cell proliferation in the lateral root cap of the Arabidopsis root. [PDF]
Unterholzner SJ +6 more
europepmc +1 more source
Accounting for animal health in efficiency analysis: An application to Swedish dairy farms
Abstract Poor animal health is a central concern in modern livestock production. Despite the necessity to incorporate animal health in efficiency analysis, the theoretical and empirical developments are limited on this subject. This article appropriately characterizes the axiomatic properties of animal health within a production framework.
Frederic Ang +3 more
wiley +1 more source
Data-driven age partitioning for pediatric serum copper: implications for reference interval interpretation. [PDF]
Pham HT +5 more
europepmc +1 more source
Crop insurance and irrigation behavior: The conditional role of pumping costs
Abstract Excessive water use for irrigation can accelerate the depletion of water resources, undermining agriculture's resilience to weather‐related shocks. Understanding how farmers make water use decisions is essential for developing effective water management policies.
Sungmin Cheu, Molly Sears
wiley +1 more source
Learning Continuous Decomposable Models Using Mutual Information and Statistical Copulas. [PDF]
Desuó Neto L +3 more
europepmc +1 more source
Phylogenomic insights into the genus Tulipa (Liliaceae): Taxonomy, evolution, and biogeography
Abstract Premise Tulips are one of the best‐known geophytes, but their taxonomy remains convoluted and their evolutionary history poorly understood. Here, we used plastid genomes to identify some issues with current classification, understand the diversification history of the genus, and identify potential species linked to historical cultivation ...
Brett Wilson +17 more
wiley +1 more source

