Abstract Objective Thalamic responsive neurostimulation (RNS) is a surgical option for patients with drug‐refractory epilepsy. However, it is unclear whether thalamic connectivity with the seizure onset zone (SOZ) has a role in clinical outcomes. Here, we aim to investigate the clinical utility of the connectivity between the SOZ and the thalamus for ...
Varun R. Subramaniam +12 more
wiley +1 more source
Abstract Objective One‐third of patients with epilepsy, particularly those with mesial temporal lobe epilepsy (MTLE), remain resistant to medication. Resective surgery, the gold standard, is highly invasive and carries significant risks. Here, using a mouse model, we explored the potential of microbeam radiation therapy (MRT), a new technique based on ...
Loan Samalens +8 more
wiley +1 more source
The MCTOT app: A publicly available tool for statistical cycle-to-threshold analysis and inference of informative but uncertainly determined qPCR data. [PDF]
Zhuang W, Liu J.
europepmc +1 more source
A Nonparametric Training Algorithm for Decentralized Binary Hypothesis Testing Networks
John Wissinger, Michael Athans
openalex +2 more sources
Abstract Recurrent seizures, the hallmark of epilepsy, are influenced by rhythms operating over multiple timescales. Chronobiology is the study of biological timing that aims to explain temporal patterns of events like seizures. Fueled by recent advances in genetics, computational modeling, and device engineering, the chronobiology of epilepsy is now a
Maxime O. Baud +4 more
wiley +1 more source
Extensions of multinomial processing tree models for continuous variables: A simulation study comparing parametric and non-parametric approaches. [PDF]
Gutkin A, Heck DW.
europepmc +1 more source
Simultaneous hypothesis testing on geographically weighted nonparametric regression (A case study: Poverty data in Sulawesi Island) [PDF]
Lilis Laome +2 more
openalex +1 more source
Depressive symptoms as independent correlates of epilepsy‐related cognitive burden
Abstract Objective This study was undertaken to assess the relationship between the severity of depression and anxiety symptoms and epilepsy‐related variables and cognitive burden in people with epilepsy (PwE), as assessed using EpiTrack. Methods We prospectively enrolled a cohort of PwE who underwent EpiTrack and evaluation by Generalized Anxiety ...
Biagio Maria Sancetta +10 more
wiley +1 more source
Multiple Contrast Tests for Count Data: Small Sample Approximations and Their Limitations. [PDF]
Pigorsch M, Hothorn LA, Konietschke F.
europepmc +1 more source
Bayesian Hypothesis Test Using Nonparametric Belief Propagation for Noisy Sparse Recovery [PDF]
Jaewook Kang, Heung-No Lee, Kiseon Kim
openalex +1 more source

