Results 171 to 180 of about 6,398 (252)

Elevation‐Dependent Permafrost Thaw on the Tibetan Plateau Delays Seasonal Discharge and Poses a Risk of Reduction in Downstream Water Availability

open access: yesEarth's Future, Volume 14, Issue 7, July 2026.
Abstract Global warming and permafrost thaw have significantly altered landscapes and hydrological conditions in permafrost regions. While site‐specific process studies have described hydrological changes during thawing, basin‐scale impact assessments and streamflow modeling remain challenging due to landscape heterogeneity and complex interactions ...
Chengwei Wan   +5 more
wiley   +1 more source

Genomic and Sex Contributions to Interindividual Variability in Pitavastatin Bioavailability

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT Aim This study investigates pharmacogenetic determinants of pitavastatin disposition using a candidate‐gene approach. Methods In 48 healthy volunteers, 138 variants across 40 genes involved in drug metabolism and transport were analysed to assess their relationship with pitavastatin pharmacokinetics, alongside the influence of sex and ...
Eva González‐Iglesias   +7 more
wiley   +1 more source

Data-Driven Chance Constrained Mixed Integer Nonlinear Bilevel Optimization via Copulas. [PDF]

open access: yesInd Eng Chem Res
Johnn SN   +5 more
europepmc   +1 more source

A New Framework to Empower Ecosystem Assessment Through the Integration of eDNA Inventories, Graph Theory and Niche Modelling

open access: yesEcology Letters, Volume 29, Issue 7, July 2026.
There is a lack of conceptual frameworks to validate the integration of eDNA and ecological network analysis into ecosystem monitoring. We propose a tool that combines eDNA inventories, graphlet‐based network analysis, ecological niche modelling and machine learning, and demonstrate that the associated topological metrics are effective for ecological ...
Benjamin Alric   +4 more
wiley   +1 more source

Serum nonmercaptalbumin to total albumin ratio and bilirubin predict ADL decline in older adults with type 2 diabetes

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 7, Page 1202-1209, July 2026.
In a longitudinal cohort of older adults with type 2 diabetes, incident ADL disability was evaluated. Higher HNA%, lower serum bilirubin, and older age independently predicted the risk of disability. Their combined assessment may offer clinically useful tools for identifying individuals at elevated risk of functional deterioration.
Yukihiro Inoguchi   +10 more
wiley   +1 more source

Association between blood pressure levels and mortality in patients with type 2 diabetes: A retrospective cohort analysis

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 7, Page 1183-1193, July 2026.
In this retrospective cohort analysis, systolic blood pressure ≥140 mmHg (vs <130) significantly increased all‐cause, cardiovascular, cerebrovascular, and diabetes mortality, whereas diastolic pressure 80–90 mmHg (vs <80) was associated with lower all‐cause and cardiovascular mortality.
Zhen‐Yu Liu   +6 more
wiley   +1 more source

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