Results 181 to 190 of about 128,596 (295)

Gut–Brain Axis Modulation by Short‐Chain Fatty Acids Exerts Disease‐Modifying Effects in a Murine Model of Drug‐Resistant Epilepsy

open access: yesAnnals of Neurology, EarlyView.
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera   +16 more
wiley   +1 more source

Causal K-Means Clustering. [PDF]

open access: yesJ R Stat Soc Series B Stat Methodol
Kim K, Kim J, Kennedy EH.
europepmc   +1 more source

Hyperacute Interleukin‐1β Production and Neutrophil Extracellular Trap Formation in the Cerebral Circulation of Stroke Patients with Large Vessel Occlusion

open access: yesAnnals of Neurology, EarlyView.
Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg   +33 more
wiley   +1 more source

Tensile Stimulation in Biorelevant Culture Conditions Enhances MSC and TPSC Tenogenesis on Aligned Electrospun Scaffolds

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro   +3 more
wiley   +1 more source

Knowledge, attitude, and practice of self-medication among adults in the central region of Saudi Arabia: a cross-sectional study. [PDF]

open access: yesFront Public Health
Aldali RJ   +5 more
europepmc   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

open access: yesAdvanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer   +5 more
wiley   +1 more source

Evaluation of Greenhouse Gas Emissions and Sludge Characteristics in Typical AAO Process WWTPs in Taihu Lake Basin, China

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study investigated sludge characteristics and greenhouse gas (GHG) emission from 16 anaerobic‐anoxic‐oxic (AAO) process wastewater treatment plants (WWTPs), 11 municipal and 5 industrial WWTPs, located in the Taihu Lake Basin, China. Influent/effluent water quality, sludge properties, operational parameters, GHG emission patterns, and ...
He Li, Zhirun Liu, Rajendra Prasad Singh
wiley   +1 more source

A statistical inference framework for FSNBLR: Modeling underdeveloped regional status in Eastern Indonesia. [PDF]

open access: yesMethodsX
Zulfadhli M   +4 more
europepmc   +1 more source

Segmental composition and nerve distribution of the brachial plexus in Galictis cuja

open access: yesThe Anatomical Record, EarlyView.
Abstract Galictis cuja is a neotropical mustelid with terrestrial locomotor habits, yet the anatomy of its brachial plexus has remained undescribed. This study characterizes the origin, organization, and distribution of the brachial plexus nerves in 15 adult specimens (30 antimeres).
Natan da Cruz de Carvalho   +6 more
wiley   +1 more source

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