Results 111 to 120 of about 15,810,178 (316)

Conductive Hydrogels for Exogenous Sensing and Cell Fate Control

open access: yesAdvanced Materials, EarlyView.
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar   +15 more
wiley   +1 more source

Order selection tests with multiply-imputed data. [PDF]

open access: yes
We develop nonparametric tests for the null hypothesis that a function has a prescribed form, to apply to data sets with missing observations. Omnibus nonparametric tests do not need to specify a particular alternative parametric form, and have power ...
Claeskens, Gerda, Consentino, Fabrizio
core  

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

Approximate Kernel-Based Conditional Independence Tests for Fast Non-Parametric Causal Discovery

open access: yesJournal of Causal Inference, 2019
Constraint-based causal discovery (CCD) algorithms require fast and accurate conditional independence (CI) testing. The Kernel Conditional Independence Test (KCIT) is currently one of the most popular CI tests in the non-parametric setting, but many ...
Strobl Eric V.   +2 more
doaj   +1 more source

Microglia Mitochondria Support Neuronal Maturation via Metabolic and Transcriptional Reprogramming in Human 3D In Vitro Brain Model

open access: yesAdvanced Science, EarlyView.
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben   +4 more
wiley   +1 more source

PARAMETRIC AND NONPARAMETRIC MARKET POWER TESTS: AN EMPIRICAL INVESTIGATION [PDF]

open access: yes
Parametric and nonparametric market power tests most commonly used to assess imperfectly competitive behavior are identified. Monte Carlo experiments are used to assess the accuracy of eight nonparametric tests.
Noelke, Corinna M., Raper, Kellie Curry
core   +1 more source

Using Non-Parametric Tests to Evaluate Traffic Forecasting Performance. [PDF]

open access: yes, 2002
This paper proposes the use of a number of nonparametric comparison methods for evaluating traffic flow forecasting techniques. The advantage to these methods is that they are free of any distributional assumptions and can be legitimately used on small ...
Chen, H.   +2 more
core  

Minimax Nonparametric Parallelism Test.

open access: yesJournal of machine learning research : JMLR, 2020
Testing the hypothesis of parallelism is a fundamental statistical problem arising from many applied sciences. In this paper, we develop a nonparametric parallelism test for inferring whether the trends are parallel in treatment and control groups.
Xing, Xin   +3 more
openaire   +2 more sources

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou   +14 more
wiley   +1 more source

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