Results 211 to 220 of about 3,204,274 (288)

Comparing Two Categorical Gini Correlations with Applications to Classification Problems. [PDF]

Stat Pap (Berl)
Hewage S, Sang Y.
europepmc   +1 more source

Expanded characterization of the valproic acid zebrafish larval model of autism spectrum disorder: Insights into dysregulation in the gut

Animal Models and Experimental Medicine, EarlyView.
Meticulous calculation of zebrafish‐equivalent therapeutic valproic acid (VPA) dosage maximized the translational value of the data. Hyposerotonergic tone underpinned an anxiety‐like outcome as a core symptom of autism spectrum disorder (ASD). Compartment‐specific dopaminergic and serotonergic dysregulation in the brain versus gut provided mechanistic ...
Lesha Pretorius, Johanna Adriana Coetzee, Alexio Pedro dos Santos, Carine Smith   +3 more
wiley   +1 more source

Select earthquake forecasting models demonstrate consistency with prospective decadal observations in California. [PDF]

Nat Commun
Bayona JA, Serafini F, Silva F, Iturrieta P, Savran WH, Herrmann M, Marzocchi W, Maechling PJ, Werner MJ.   +8 more
europepmc   +1 more source

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

Annals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca, Adrià Vilaseca‐Capel, Judith Cantó‐Santos, Ester Tobías, Félix Andújar‐Sánchez, Laia Farré‐Tarrats, Frederic Tort, Carles Rentero, Carlos Enrich, Virginia López, Juan R. Tejedor, Anna Esteve‐Codina, Cristina Núñez de Arenas, Pedro J. Moreno‐Lozano, José C. Milisenda, Mar O'Callaghan, Teresa García‐Silva, Montserrat Morales‐Conejo, Mario F. Fraga, Rafael Artuch, Miguel Á. Martín, José M. Cuezva, Ana Matas, Glòria Garrabou, Mariona Guitart‐Mampel   +24 more
wiley   +1 more source

Early diagnostic value of serum procalcitonin, C-reactive protein, white blood cell count and the neutrophil percentage in bacterial and fungal bloodstream infections. [PDF]

BMC Immunol
Zhai S, Luo C.
europepmc   +1 more source

Rate and Shape of Functional Decline in Amyotrophic Lateral Sclerosis Identify Clinically Distinct Amyotrophic Lateral Sclerosis Phenotypes

Annals of Neurology, EarlyView.
Objective The ALS Functional Rating Scale–Revised decline rate compresses trajectory shape into a single number, potentially missing distinct phenotypes. We tested whether shape identifies phenotypes that rate does not distinguish, and whether post‐hoc analysis recovers a hidden ultrarapid subgroup. Methods From the Piemonte and Valle d'Aosta register (
Andrea Calvo, Cristina Moglia, Antonio Canosa, Umberto Manera, Elisabetta Zucchi, Giulia Gianferrari, Ilaria Martinelli, Gabriele Mora, Sara Cabras, Francesca Palumbo, Enrico Matteoni, Giorgio Pellegrino, Emilio Minerva, Daniela Pascariu, Stefano Callegaro, Fabrizio D'Ovidio, Rosario Vasta, Letizia Mazzini, Fabiola De Marchi, Jessica Mandrioli, Adriano Chiò   +20 more
wiley   +1 more source

The Nature of Cell‐Penetrating Poly(disulfide)s

Angewandte Chemie, EarlyView.
The mode of action of cell‐penetrating poly(disulfide)s (CPDs) is elucidated to understand thiol‐mediated uptake (TMU) in general and guide future efforts to control cellular entry for chemicals delivery and pathogen defense. ABSTRACT Cell‐penetrating poly(disulfide)s (CPDs) are the most popular thiol‐mediated uptake (TMU) tools for delivering attached
Saidbakhrom Saidjalolov, Giacomo Renno, Yuheng Zhang, Michael Cognet, Justin Neuman, Andreas Hennig, Naomi Sakai, Stefan Matile   +7 more
wiley   +2 more sources

A Comprehensive In Vitro Approach for Assessing the Physiological Degradation of Medical Implants: The Silkothane Arteriovenous Graft Case Study

Advanced NanoBiomed Research, EarlyView.
Evaluating the degradation of absorbable medical devices in vitro demands physiologically relevant conditions. This study presents a comprehensive framework applied to a three‐layered silk fibroin/polyurethane arteriovenous graft, employing human enzymes at physiological concentrations over 6 months. Multiparametric analyses of both graft structure and
Cristina Oldani, Alice Caldiroli, Federica Barzaghi, Nina Bono, Gabriele Candiani, Stefania Adele Riboldi   +5 more
wiley   +1 more source

The Effectiveness of the Revised PEACE Pack With Primary School Students: A Positive Approach to Bullying Reduction and Wellbeing. [PDF]

Health Promot J Austr
Shute RH, Slee PT.
europepmc   +1 more source

In Vivo Nb4C3Tx MXene‐Assisted Photothermal Therapy of Melanoma in Mice

Advanced NanoBiomed Research, EarlyView.
Nb4C3Tx MXene converts pulsed 1064 nm irradiation into localized heat, producing concentration‐ and time‐dependent melanoma cell killing in vitro and suppressing tumor growth in mice. Histology reveals extensive tumor damage, macrophage‐associated material clearance, and no detectable persistent deposits in examined visceral organs, supporting Nb4C3Tx ...
Anton Roshchupkin, Benjamin Chacon, Gulnaz Gahramanova, Inna Chorna, Zhanna Klishchova, Anastasia Konieva, Ilya Yanko, Andrii Liutyi, Milena Yalyzhko, Ivan Baginskiy, Veronika Zahorodna, Júlio Sílvio de Sousa Bueno Filho, Erfan Rezvani Ghomi, Igor Panko, Tetiana Shapochka, Oksana Sulaieva, Oleksandr Solodovnyk, Lucia Gemma Delogu, Oleksiy Gogotsi, Laura Fusco, Sergiy Kyrylenko, Yury Gogotsi, Maksym Pogorielov   +22 more
wiley   +1 more source