Results 61 to 70 of about 3,713 (136)
Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg +33 more
wiley +1 more source
On the importance of including both sexes in animal studies – insights from home‐cage monitoring
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater +12 more
wiley +1 more source
ABSTRACT Background This cross‐sectional study aimed to identify symptom profiles and their associated factors in Chinese patients with multiple myeloma, thereby providing an evidence‐based foundation for developing targeted symptom management strategies. Methods Patients with multiple myeloma were recruited via convenience sampling from the hematology
Ting Wang +7 more
wiley +1 more source
In this randomized, double‐blind, placebo‐controlled trial, 8‐week supplementation with Pediococcus acidilactici PA53 significantly improved stool form in adults with functional constipation. PA53 supplementation was associated with changes in inflammatory markers and gut microbiota, including increased Pediococcus abundance.
Yuhan Xia +5 more
wiley +1 more source
Nonstationarity in wildlife disease dynamics: insights from the prairie dog–plague system
Ecological relationships often vary in strength and direction across ecosystems, a pattern that has become increasingly evident as ecology expands to broader spatial and temporal scales. Although such nonstationarity – the changing effect of predictor variables across spatiotemporal contexts – is widely acknowledged in ecological research, it has ...
Gabriel M. Barrile +6 more
wiley +1 more source
An explainable machine‐learning framework predicts complete stress–strain behavior and key mechanical properties of FFF‐printed ULTEM 9085 from four printing parameters. Extra Trees delivered the most accurate and stable predictions, while SHAP and LIME clarified how each parameter influences material performance.
Md Asif Hasan +7 more
wiley +1 more source
Large Covariance Matrix Estimation by Penalized Log‐Det Heuristics
ABSTRACT We study covariance estimation in high‐dimensional approximate factor models with a sparse residual covariance. The estimator combines a log‐det loss with nuclear‐norm and off‐diagonal ℓ1$$ {\mathrm{\ell}}_1 $$ penalties on a sample‐normalized covariance scale.
Enrico Bernardi, Matteo Farnè
wiley +1 more source
Abstract Statistical hypothesis testing (SHT) is widely employed across numerous scientific disciplines, and a clear understanding of its underlying logic is essential for the broader scientific community. Here, drawing upon both epistemological and statistical perspectives, we aim to clarify—primarily for educational purposes—the logical relationship ...
Maria Cristina Amoretti +1 more
wiley +1 more source
ABSTRACT Anchored on the sustainable development goals (SDGs) and the Paris Agreement, which seek to limit the global average temperature to well below 2°C above pre‐industrial levels and pursue efforts to limit the temperature to 1.5°C, this study investigates how green energy finance and environmental taxes affect environmental quality, with an ...
Mohammed Musah +4 more
wiley +1 more source
Abstract Intensifying wet extremes under continued warming threaten water security and ecosystem functioning by perturbing land–atmosphere water fluxes. Yet, the watershed‐scale controls on how wet‐event intensity and duration translate into changes in fractional evapotranspiration (fET) remain poorly constrained at global scales.
Maheshwari Neelam
wiley +1 more source

