Results 141 to 150 of about 41,960 (230)

The interplay between mRNA translation and nonsense-mediated decay in AUG-proximal nonsense-mutated transcripts [PDF]

, 2014
Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that recognizes and rapidly degrades mRNAs containing premature termination codons (PTC).
Romão, Luísa
core  

p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells [PDF]

, 2017
Cheruiyot, Abigael, Flanagan, Kevin C., Nickless, Andrew, Piwnica-Worms, David, Stewart, Sheila A., You, Zhongsheng   +5 more
core   +2 more sources

Loss of function mutations in RP1 are responsible for retinitis pigmentosa in consanguineous familial cases. [PDF]

, 2016
PurposeThis study was undertaken to identify causal mutations responsible for autosomal recessive retinitis pigmentosa (arRP) in consanguineous families.MethodsLarge consanguineous families were ascertained from the Punjab province of Pakistan.
Akram, Javed, Ali, Shahbaz, Assir, Muhammad Zaman, Ayyagari, Radha, Gottsch, Alexander DH, Hejtmancik, J Fielding, Kabir, Firoz, Khan, Shaheen N, Naeem, Muhammad Asif, Riazuddin, S Amer, Riazuddin, Sheikh, Ullah, Inayat   +11 more
core   +1 more source

Nonsense-mediated mRNA decay in collagen X

, 2010
Genetic disorders are a major cause of human disability and disease. It has been estimated that 5-10% of the population is affected by an inherited disorder during their lifetime, and a startling 70% of pediatric admissions involve a genetic component.
openaire   +1 more source

[Nonsense-mediated mRNA decay in plants].

[Nonsense-mediated mRNA decay in plants].
identifier:oai:t2r2.star.titech.ac.jp ...
openaire   +1 more source

Inhibition of nonsense-mediated mRNA decay reduces the tumorigenicity of human fibrosarcoma cells. [PDF]

NAR Cancer, 2023
Nasif S, Colombo M, Uldry AC, Schröder MS, Schröder MS, de Brot S, Mühlemann O.   +6 more
europepmc   +2 more sources

Nonsense-mediated mRNA decay safeguards telomeres in pluripotent stem cells. [PDF]

Nat Cell Biol
Markiewicz-Potoczny M, Lee SY, Chatterjee S, Mabin JW, Zinsser A, Sandhu R, Tricola G, Hogg JR, Lazzerini Denchi E.   +8 more
europepmc   +1 more source

Dynamic RNA binding and unfolding by nonsense-mediated mRNA decay factor UPF2. [PDF]

RNA
Szeto JA, Vega MV, Mailliot J, Orriss G, Sun L, Bufton JC, Powers KT, Yadav SKN, Berger I, Schaffitzel C.   +9 more
europepmc   +2 more sources

The nonsense-mediated mRNA decay factor Upf3 negatively regulates bulk autophagy progression in <i>Saccharomyces cerevisiae</i>. [PDF]

Autophagy Rep
Tasmi TA, Solomon E, Avogo EW, Badenahalli Narasimhaiah S, Delorme-Axford E.   +4 more
europepmc   +1 more source

Integrative and accurate annotations enhance current nonsense-mediated mRNA decay rules. [PDF]

Nucleic Acids Res
Iha H, Kikutake C, Suyama M.
europepmc   +1 more source