Results 91 to 100 of about 27,331 (253)
European Review, 2000 Research councils are under pressure and some are responding pro-actively. This has implications for their functioning as ‘aggregation machines’ taking in proposals and churning out judgements and decisions. Five scenarios of possible futures for research councils in the world of strategic science are laid out, with ...
openaire +3 more sources
On Determination Method for Resolution of Secondary Electron Images in Scanning Electron Microscopy
Advanced Science, EarlyView.An idealized SEM, termed Rayleigh's microscope, is constructed by Monte Carlo simulation to represent imaging conditions that just satisfy the Rayleigh criterion. Based on this physically defined model, sharpness–resolution conversion curves are established and combined with the Rose criterion, enabling automated resolution evaluation from practical ...
Tongfang Yang, Yanbo Zou, Zejun Ding
wiley +1 more source
Advanced Science, EarlyView.This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li +4 more
wiley +1 more source
Inspired by the early Wittgenstein\u27s concept of nonsense (meaning that which lies beyond the limits of language), we investigate two different types of nonsense: formal nonsense and pragmatic nonsense.
Abrahão, Felipe S. +2 more
core +2 more sources
Advanced Science, EarlyView.TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang +18 more
wiley +1 more source
Frontiers in Endocrinology, 2017 BackgroundActivity-dependent neuroprotective protein (ADNP) is one of the most prevalent de novo mutated genes in syndromic autism spectrum disorders, driving a general interest in the gene and the syndrome.AimThe aim of this study was to provide a ...
Illana Gozes +7 more
doaj +1 more source
, 2005 Nonsense-mediated RNA decay (NMD) is an evolutionary conserved system of RNA surveillance that detects and degrades RNA transcripts containing nonsense mutations.
Claudio Alonso (4462075)
core
Genetic Code Expanded T Cell for Controllable Immunotherapy
Advanced Science, EarlyView.Our GCE‐CAR‐T cells enables tight, dose‐dependent, and function‐preserving control of CAR expression at the translational level through amber codon suppression and genetic incorporation of ncAA. ABSTRACT Chimeric antigen receptor (CAR)‐T cell therapy has demonstrated curative potential against hematologic malignancies, but its clinical application ...
Xue Wang +4 more
wiley +1 more source
Borboletabirinto da poesia de Ondjaki
Études romanes de Brno, 2018 Este estudo pretende mostrar a faceta poética da obra do jovem escritor angolano Ondjaki. Essa característica perpassa por toda a sua obra, tanto na poesia como na prosa, e o objetivo que nós propomos é analisar e mostrar o poetismo desta obra literária.
Kateřina Ritterová
doaj +1 more source
Nonsense and other senses : regulated absurdity in literature
, 2009 This book deals with a topic that is gaining increasing critical attention, the literature of nonsense and absurdity. The volume gathers together twenty-one essays on various aspects of literary nonsense, according to criteria that are deliberately ...
core