Results 251 to 260 of about 142,808 (332)

Apremilast in Japanese patients with palmoplantar pustulosis: A randomized, Phase 3 trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In this Phase 3 trial of Japanese patients with moderate to severe PPP (NCT05174065), significantly more patients achieved PPPASI‐50 at Week 16 with apremilast versus placebo. Patient‐reported outcomes, including pruritus and pain/discomfort, also showed significantly greater decreases at Week 16 with apremilast versus placebo.
Tadashi Terui, Yukari Okubo, Satomi Kobayashi, Akimichi Morita, Shinichi Imafuku, Yayoi Tada, Masatoshi Abe, Bruce Strober, Melinda Gooderham, Wendy Zhang, Junichiro Shimauchi, Masafumi Yaguchi, Takeshi Kimura, Ryuichi Ogawa, Hamid Amouzadeh, Masamoto Murakami   +15 more
wiley   +1 more source

The urinary albumin‐to‐creatinine ratio can direct personalized prevention and treatment for cardiovascular and chronic kidney disease

Journal of Internal Medicine, EarlyView.
Abstract Increased urinary albumin excretion is a strong predictor for cardiovascular events in persons with and without decreased glomerular filtration rate and can be assessed with the urinary albumin‐to‐creatinine ratio (UACR), which is a selective, sensitive, and convenient method for patients.
Holly J. Kramer, George L. Bakris
wiley   +1 more source

Efficacy of core muscle strengthening training around the knee compared to oral nonsteroidal anti-inflammatory drugs in early-stage knee osteoarthritis patients: protocol for a randomized controlled trial. [PDF]

Trials
Wei C, Wang X, Xiong Y, Song W, Guo X, Yu J, Jiang W, Zhao Y, Yang Z, Sun Z, Huang R, Sun Y.   +11 more
europepmc   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Do nonsteroidal anti-inflammatory drugs increase the risk of atrial fibrillation after non-cardiac surgery? Insights from translational and clinical research. [PDF]

J Anesth Analg Crit Care
Laou E, Mitta S, Voutsadaki E, Ntalarizou N, Tselioti P, Cortegiani A, Chalkias A.   +6 more
europepmc   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Cardiovascular-Kidney-Metabolic Effects: Steroidal and Nonsteroidal Mineralocorticoid Receptor Antagonists. [PDF]

Rev Cardiovasc Med
Bozkurt B, Januzzi JL, Bansal S.
europepmc   +1 more source

Evaluation of buprenorphine as optimisation of postoperative analgesia in feral cats undergoing ovariohysterectomy under field conditions

Journal of Small Animal Practice, EarlyView.
Objectives The objective of this prospective, randomised, blinded, observational clinical study was to investigate the effect of subcutaneously administered buprenorphine on postoperative pain in female feral cats undergoing ovariohysterectomy as part of a trap‐neuter‐return programme.
V. Heitzmann, A. Diggelmann, E. Goldinger, A. Schiele   +3 more
wiley   +1 more source

A Case of Corneal Melting Associated with Topical Diclofenac After Phacovitrectomy for Macular Pucker in a Patient with Rheumatoid Arthritis. [PDF]

Int Med Case Rep J
Tripodi S, Maggio E, Arena F, Pertile G.
europepmc   +1 more source

Differentially Expressed Salivary miRNAs in Temporomandibular Disorders

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective Temporomandibular disorders (TMDs) are heterogeneous conditions of unclear aetiology involving the temporomandibular joint, masticatory muscles and neural tissues. Limited understanding of their pathogenesis hampers accurate diagnosis and targeted treatment. Therefore, this study aimed to identify salivary microRNA (miRNA) signatures
Karolina Elżbieta Kaczor‐Urbanowicz, Mohammad Aziz, Holly Wilhalme, Sharon Aronovich, Elizabeth Rae Hatfield, Tara Aghaloo, Sherwin Arman, Aida Mohammadi, Mohammed Husain, Sotirios Tetradis, David Elashoff, Matteo Pellegrini, David T. W. Wong, Sunil Kapila   +13 more
wiley   +1 more source