Results 271 to 280 of about 142,808 (332)

Cilofexor, a Nonsteroidal FXR Agonist, in Patients With Noncirrhotic NASH: A Phase 2 Randomized Controlled Trial

Hepatology, 2020
We evaluated the safety and efficacy of cilofexor (formerly GS‐9674), a small‐molecule nonsteroidal agonist of farnesoid X receptor, in patients with nonalcoholic steatohepatitis (NASH).
K. Patel, S. Harrison, M. Elkhashab, J. Trotter, R. Herring, S. Rojter, Z. Kayali, V. Wong, S. Greenbloom, S. Jayakumar, M. Shiffman, B. Freilich, E. Lawitz, E. Gane, Eliza Harting, Jun Xu, A. Billin, C. Chung, C. Djedjos, G. Subramanian, R. Myers, M. Middleton, M. Rinella, M. Noureddin   +23 more
semanticscholar   +1 more source

Nonsteroidal anti-inflammatory drugs (NSAIDs)

Pharmacology Mind Maps for Medical Students and Allied Health Professionals, 2019
U Dose reduction or cessation may be considered for all patients taking NSAIDs whose symptoms are under control and are relatively stable. U Some patients may find intermittent use of NSAIDs as effective as continuous use.
Ida Ghlichloo, Valerie A. Gerriets
semanticscholar   +1 more source

Nonsteroidal Anti-Inflammatory Drugs

Veterinary Clinics of North America: Equine Practice, 1993
NSAIDs' mechanism of action by inhibiting the synthesis of prostanoids accounts for both their therapeutic and toxic effects. They are commonly used in acute and chronic musculoskeletal and soft-tissue conditions. Adverse reactions include gastrointestinal disturbances and hypoproteinemia. Their pharmacologic effect seems to have a longer duration than
openaire   +4 more sources

A Nonsteroidal Androgen

Science, 1960
2-Acetyl-7-oxo-1, 2, 3, 4, 4a, 4b, 5, 6, 7, 9, 10, 10a-dodecahydrophenanthrene possesses androgenic activity when applied directly to the chick's comb. This action is in addition to the antiandrogenic activity previously reported for this compound. This is the first demonstration of androgenic activity by a compound not possessing the steroid nucleus.
openaire   +2 more sources

Nonsteroidal Anti-inflammatory Drugs

Clinics in Geriatric Medicine, 1990
Although the increased need for studies assessing the influence of age on the pharmacokinetics and pharmacodynamics of all drugs has been emphasized, relatively little is known about NSAIDs in the elderly. The pharmacokinetics of some NSAIDs have been examined in elderly subjects; unfortunately, recent data indicate that much of the earlier information
M D, Murray, D C, Brater
openaire   +2 more sources

Role of Nonsteroidal Antiinflammatory Drugs in the Association Between Osteoarthritis and Cardiovascular Diseases: A Longitudinal Study

Arthritis & Rheumatology, 2019
To elucidate the role of nonsteroidal antiinflammatory drugs (NSAIDs) in the increased risk of cardiovascular disease (CVD) among osteoarthritis (OA) patients.
M. Atiquzzaman, M. E. Karim, J. Kopec, H. Wong, A. Anis   +4 more
semanticscholar   +1 more source