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Nonsteroidal Anti-inflammatory Drugs
Archives of Internal Medicine, 1984Over the past decade, many new nonsalicylate, nonsteroidal anti-inflammatory drugs (NSAIDs) have been introduced in the United States. These include fenoprofen, ibuprofen, meclofenamate, naproxen, piroxicam, sulindac, and tolmetin in addition to indomethacin and phenylbutazone, which were previously available.
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Nonsteroidal anti-inflammatory drugs and antihypertensives
The American Journal of Medicine, 1991Approximately 60 million people in the United States have hypertension (BP greater than or equal to 140/90 mm Hg), 40 million have arthritis clinically suitable for nonsteroidal anti-inflammatory drug (NSAID) therapy, and millions take NSAIDs for nonarthritic conditions, creating considerable potential for concomitant administration of NSAIDs and ...
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Nonsteroidal Anti-Inflammatory Drugs, and Hypertension
Annals of Internal Medicine, 1988Excerpt To the Editor:That the effect of nonsteroidal anti-inflammatory drugs on blood pressure remains a concern is reflected in the recent article by Radick and colleagues (1).
E S, Kisch, B, Fischel, M, Yaron
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Nonsteroidal anti-inflammatory drug gastropathy
Gastroenterology, 2000By inhibiting prostaglandin synthesis, nonsteroidal anti-inflammatory drugs (NSAIDs) compromise gastroduodenal defense mechanism including blood flow and mucus/bicarbonate secretion. This has led to NSAIDs being the most widely reported drug cause of adverse events.
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Nonsteroidal Anti-inflammatory Drugs and the Gut
Southern Medical Journal, 1996Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for analgesic, anti-inflammatory, and antithrombotic indications. Such use carries the risk of significant side effects on nontarget organs, especially the gut. Some of these effects may be serious, especially among the elderly, whose NSAID use is proportionately greatest.
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The Nonsteroidal Anti-Inflammatory Drugs Controversy
Gastroenterology Clinics of North America, 2000The relationship between NSAIDs and H. pylori as risk factors for the development of peptic ulcer is complex and controversial. In the case of duodenal ulcers in NSAID users, there now is enough information to suggest that eradication of H. pylori usually is worthwhile.
N D, Yeomans, G, Garas, C J, Hawkey
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Toxicity of the nonsteroidal anti-inflammatory drugs
Current Opinion in Rheumatology, 1991The nonsteroidal anti-inflammatory drugs continue to be prescribed frequently around the world to palliate the pain and inflammation associated with various medical conditions. These are a heterogenous group of drugs with similar mechanisms of action, yet they are very different chemically and at times possess different potential risks for toxicity ...
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Nonsteroidal Anti-inflammatory Drugs and the Kidney
Current Sports Medicine Reports, 2002The use of NSAIDs before and during exercise has been causally linked to acute renal failure in case study reports. Fortunately, the incidence of renal failure associated with exercise is low, even in athletes who habitually or excessively use NSAIDs. Based on the physiology of the kidney and the pharmaceutical properties of NSAIDs, excessive NSAID use
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Nonsteroidal Anti-Inflammatory Drug Enteropathy
Gastrointestinal Endoscopy Clinics of North America, 1999Although the upper gastrointestinal toxicity of non-steroidal anti-inflammatory drugs( NSAID) is well documented, the appreciation that NSAID damage extends beyond the duodenum is less well recognized. Recent data suggests that clinically important ulceration can be found in the small intestine, and may lead to complications such as obscure bleeding ...
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Nonsteroidal Anti-Inflammatory Drugs
Pharmacology, 2008Satish K. Srivastava, Kota V. Ramana
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