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Effects of Cyclooxygenase Inhibitors on Apoptotic Neuroretinal Cells
Biomarker Insights, 2008 Glaucoma is characterized by a loss of retinal ganglion cells (RGC) which is associated with a decrease of visual function. Neuroprotective agents as a new therapeutic strategy could prevent the remaining neurons from apoptotic cell death.
Anja-Kristina Brust +4 more
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Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy [PDF]
Frontiers in Immunology, 2021 Chimeric antigen receptor T (CAR-T) cells targeting CD19 came into clinical practice for the treatment of B cell lymphoma in 2018. However, patients being treated for B cell lymphoma often suffer from comorbidities such as chronic pain, cardiovascular ...
Mingya Yang +24 more
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Stimulatory Action of Cyclooxygenase Inhibitors on Hematopoiesis: A Review [PDF]
Molecules, 2012 The presented review summarizes experimental data obtained with a mouse model when investigating the relationship between inhibition of prostaglandin production and hematopoiesis.
Lenka Weiterová +4 more
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Conjugation of Cisplatin Analogues and Cyclooxygenase Inhibitors to Overcome Cisplatin Resistance [PDF]
ChemMedChem, 2015 Wilma Neumann, Matthias Scholz
exaly +2 more sources
Cyclooxygenase-2 Inhibitors [PDF]
Anesthesia & Analgesia, 2003 Background and Summary— Selective cyclooxygenase (COX)-2 inhibitors are increasingly being used in place of “conventional” nonsteroidal anti-inflammatory drugs (NSAIDs). This is because they are just as effective as NSAIDs in relieving arthritic pain and yet less gastrotoxic.
Graeme J, Hankey, John W, Eikelboom
+9 more sources
Docking studies of some pyrazole containing compounds in the cyclooxygenase-2 active site [PDF]
Arhiv za farmaciju, 2023 Whereas nonselective nonsteroidal anti-inflammatory drugs, such as aspirin, ibuprofen and diclofenac, inhibit both cyclooxygenase-1 and cyclooxigenase-2 enzymes, selective inhibitors target cyclooxygenase-2, which is overexpressed in inflammation, but ...
Savić Jelena +3 more
doaj
The overexpression of COX 2 in Wilms’ tumor [PDF]
Reviews in Clinical Medicine, 2014 Cyclooxygenase 2 has become an important pharmacological target in anticancer therapy due to the over expression of COX 2 in pathological conditions. Wilms’ tumor is a common kidney cancer in children which has shown an increase in COX 2 enzyme level ...
Sara Hashemi
doaj +3 more sources
Journal of Applied Oral Science, 2010 Prostaglandins control osteoblastic and osteoclastic function under physiological or pathological conditions and are important modulators of the bone healing process.
Ricardo Nogueira Fracon +3 more
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Cyclooxygenase (COX) Inhibitors and the Intestine [PDF]
Journal of Veterinary Internal Medicine, 2007 Abstract Nonsteroidal anti-inflammatory drugs (NSAIDs) have long been used for the treatment of pain and inflammation because of their inhibitory effects on cyclooxygenase (COX). For almost as long as NSAIDs have been in use, multiple adverse effects have been noted.
Dianne, Little +2 more
openaire +2 more sources
Cyclooxygenase (COX) Inhibitors and the Newborn Kidney
Pharmaceuticals, 2012 This review summarizes our current understanding of the role of cyclo-oxygenase inhibitors (COXI) in influencing the structural development as well as the function of the developing kidney.
Wei Qi +3 more
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