Effect of cyclooxygenase inhibitors on gentamicin-induced nephrotoxicity in rats [PDF]
Brazilian Journal of Medical and Biological Research, 2004 The frequent use of nonsteroidal anti-inflammatory drugs (NSAID) in combination with gentamicin poses the additional risk of nephrotoxic renal failure.
Hosaka E.M. +3 more
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Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy [PDF]
Frontiers in Immunology, 2021 Chimeric antigen receptor T (CAR-T) cells targeting CD19 came into clinical practice for the treatment of B cell lymphoma in 2018. However, patients being treated for B cell lymphoma often suffer from comorbidities such as chronic pain, cardiovascular ...
Mingya Yang +24 more
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Stimulatory Action of Cyclooxygenase Inhibitors on Hematopoiesis: A Review [PDF]
Molecules, 2012 The presented review summarizes experimental data obtained with a mouse model when investigating the relationship between inhibition of prostaglandin production and hematopoiesis.
Lenka Weiterová +4 more
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The role of cyclooxygenase inhibitors in lipopolysaccharide-induced hypophagia in chicken
Czech Journal of Animal Science, 2015 Previous studies showed that cyclooxygenase 1 (COX) enzyme has an important role in lipopolysaccharide (LPS)-induced hypophagia in mammals but the effect of COX on LPS-induced hypophagia has not been studied in avian species.
M. Zendehdel +3 more
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Acanthamoeba castellanii: Non-Steroidal Anti-Inflammatory Drugs Affect Adhesion, Motility, and Encystment, Suggesting a Link with a gp63-like Protein Candidate [PDF]
PathogensAcanthamoeba castellanii, an opportunistic free-living amoeba, causes severe infections including Acanthamoeba keratitis. This exploratory study evaluated whether three non-steroidal anti-inflammatory drugs (NSAIDs)—acetylsalicylic acid, ibuprofen, and ...
Verónica I. Hernández-Ramírez +11 more
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In situ click chemistry generation of cyclooxygenase-2 inhibitors
Nature Communications, 2017 Traditional inflammation and pain relief drugs target both cyclooxygenase 1 and 2 (COX-1 and COX-2), causing severe side effects. Here, the authors use in situ click chemistry to develop COX-2 specific inhibitors with high in vivo anti-inflammatory ...
Atul Bhardwaj +3 more
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Do Different Cyclooxygenase Inhibitors Impair Rotator Cuff Healing in a Rabbit Model?
Chin Med J (Engl), 2015 Yi Lu +5 more
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Cyclooxygenase-2 Inhibitors [PDF]
Anesthesia & Analgesia, 2003 Background and Summary— Selective cyclooxygenase (COX)-2 inhibitors are increasingly being used in place of “conventional” nonsteroidal anti-inflammatory drugs (NSAIDs). This is because they are just as effective as NSAIDs in relieving arthritic pain and yet less gastrotoxic.
Kristi W, Kelley, Leigh Ann, Ramsey
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Docking studies of some pyrazole containing compounds in the cyclooxygenase-2 active site [PDF]
Arhiv za farmaciju, 2023 Whereas nonselective nonsteroidal anti-inflammatory drugs, such as aspirin, ibuprofen and diclofenac, inhibit both cyclooxygenase-1 and cyclooxigenase-2 enzymes, selective inhibitors target cyclooxygenase-2, which is overexpressed in inflammation, but ...
Savić Jelena +3 more
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Cyclooxygenase inhibitors use is associated with reduced risk of esophageal adenocarcinoma in patients with Barrett’s esophagus: a meta-analysis [PDF]
British Journal of Cancer, 2014 Si‐Si Zhang +9 more
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