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Nonsteroidal Anti-Inflammatory Drugs
2010PreviewPatients with moderately severe pain or inflammation often find nonsteroidal anti-inflammatory drugs (NSAIDs) to be very beneficial. However, use of multiple NSAIDs, long-term NSAID therapy, or concomitant use of certain agents, such as corticosteroids or anticoagulants, can cause serious adverse side effects, especially in elderly patients ...
Anne M Andrews +136 more
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Nonsteroidal anti-inflammatory drugs (NSAIDs)
Pharmacology Mind Maps for Medical Students and Allied Health Professionals, 2019U Dose reduction or cessation may be considered for all patients taking NSAIDs whose symptoms are under control and are relatively stable. U Some patients may find intermittent use of NSAIDs as effective as continuous use.
Ida Ghlichloo, Valerie A. Gerriets
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Nonsteroidal Anti-Inflammatory Drug Enteropathy
Gastrointestinal Endoscopy Clinics of North America, 1999Although the upper gastrointestinal toxicity of non-steroidal anti-inflammatory drugs( NSAID) is well documented, the appreciation that NSAID damage extends beyond the duodenum is less well recognized. Recent data suggests that clinically important ulceration can be found in the small intestine, and may lead to complications such as obscure bleeding ...
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Nonsteroidal anti-inflammatory drug gastropathy
Gastroenterology, 2000By inhibiting prostaglandin synthesis, nonsteroidal anti-inflammatory drugs (NSAIDs) compromise gastroduodenal defense mechanism including blood flow and mucus/bicarbonate secretion. This has led to NSAIDs being the most widely reported drug cause of adverse events.
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Nonsteroidal Anti-Inflammatory Drug Gastropathy
Gastrointestinal Endoscopy Clinics of North America, 1996NSAID gastropathy is characterized by subepithelial hemorrhages, erosions, and ulcers. Approximately half of patients taking NSAIDs regularly have gastric erosions and 10% to 30% have gastric ulcers. Although gastric lesions are common at endoscopy, clinically significant problems are uncommon.
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Nonsteroidal anti-inflammatory drug toxicity
Current Opinion in Rheumatology, 1993The nonsteroidal anti-inflammatory drugs continue to be a mainstay of therapy for patients with chronic pain and inflammation. Because large numbers of these drugs are prescribed, even the most unusual adverse reactions are not uncommon. During the past year several reviews have appeared on the problems of nonsteroidal anti-inflammatory drug-induced ...
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Pharmacogenomics (London), 2018
Nonsteroidal anti-inflammatory drugs are the medications most frequently involved in hypersensitivity reactions to drugs. These can be induced by specific immunological and nonimmunological mechanisms, being the latter the most frequent.
M. C. Plaza-Serón +3 more
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Nonsteroidal anti-inflammatory drugs are the medications most frequently involved in hypersensitivity reactions to drugs. These can be induced by specific immunological and nonimmunological mechanisms, being the latter the most frequent.
M. C. Plaza-Serón +3 more
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Nonsteroidal Anti-Inflammatory Drugs
New England Journal of Medicine, 1974Indomethacin Indomethacin (Indocin), although very different chemically from phenylbutazone, shares much of its therapeutic spectrum.
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Nonsteroidal anti-inflammatory drugs
Reactions Weekly, 2014NSAIDs act through inhibition of cyclooxygenase enzyme (COX-1 and COX-2), thus inhibiting prostaglandin synthesis. Arachidonic acid is a polyunsaturated fatty acid that is metabolised into prostaglandins (G2, H2) and prostanoids (E2, D2, F2α, I2 and thromboxane A2). Prostanoids act via cell membrane receptors.
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Nonsteroidal Anti-inflammatory Drugs as Emerging Contaminants
Microbiology, 2020E. Tyumina +3 more
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