Results 61 to 70 of about 84,403 (307)

Correlations between electrochemical behaviors and DNA photooxidative properties of non-steroïdal anti-inflammatory drugs and their photoproducts [PDF]

, 2012
Alkali-labile lesion to DNA photosensitized, via an electron transfer mechanism, by three non-steroidalanti-inflammatorydrugs (NSAIDs), ketoprofen, tiaprofenic acid and naproxen and their photoproducts during drug photolysis, was investigated using 32P ...
Latapie, Laure, Hajj, Viviane, Fabre, Paul-Louis, Noirot, Arielle, Sartor, Valérie, Michaud, Sandra, Chouini-Lalanne, Nadia   +6 more
core   +1 more source

The impact of anti-inflammatory drugs on facial odontogenic cellulitis in children: a cross-sectional study in France

BDJ Open
Objective Dental caries is defined by the WHO as a multifactorial non-communicable disease. If left untreated, it can progress to abscesses and then head and neck odontogenic cellulitis. It requires immediate, appropriate, and interdisciplinary treatment.
Lucille Poure, Caroline Delfosse, Thomas Trentesaux, Fleur Maury, François Dubos, Romain Nicot, Thomas Marquillier   +6 more
doaj   +1 more source

Nonsteroidal anti‐inflammatory drug gastropathy – is it preventable? [PDF]

Australian and New Zealand Journal of Medicine, 1992
Non-steroidal anti-inflammatory drugs (NSAIDs) are associated with a wide spectrum of side effects, including those involving renal, hepatic and haematological function and skin rashes. It is however the gastrointestinal effects of NSAIDs which are most serious and common.
Brooks, P. M., Yeomans, N. D.
openaire   +5 more sources

Evidence That Links Loss of Cyclooxygenase-2 With Increased Asymmetric Dimethylarginine Novel Explanation of Cardiovascular Side Effects Associated With Anti-Inflammatory Drugs [PDF]

, 2014
Background—Cardiovascular side effects associated with cyclooxygenase-2 inhibitor drugs dominate clinical concern. Cyclooxygenase-2 is expressed in the renal medulla where inhibition causes fluid retention and increased blood pressure.
Warner, Timothy D., Mackenzie, L, Wang, Zhen, Armstrong, PCJ, Mitchell, JA, Kirkby, NS, Al’Yamani, Malak, Knowles, R, Al'Yamani, Malak, Armstrong, Paul C. J., Nuesing, RM, Knowles, Rebecca, Tomlinson, James A.P., Mitchell, Jane A., Mackenzie, Louise; id_orcid, Ahmetaj-Shala, Blerina, Wang, Z, Mackenzie, Louise, Al'Yamani, M, Ahmetaj-Shala, B, Mazi, S, Leiper, J, Nusing, Rolf M., Tomlinson, JAP, Tomlinson, James A. P., Mazi, Sarah, Mazi, Sara, Kirkby, Nicholas S., Armstrong, Paul C.J., Tucker, Arthur T., Warner, TD, Leiper, James, Tucker, AT   +32 more
core   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Therapy for Myhre Syndrome: Goals, Misconceptions, and Current Agents

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre Syndrome (MYHRS, MIM #139210) is a rare, multisystem connective tissue disorder caused by recurrent heterozygous gain‐of‐function pathogenic variants in the SMAD4 gene, a key player in TGF‐β signaling and a regulator of extracellular matrix homeostasis.
Alessandro De Falco, Alfonso Manuel D'Alessio, Nicola Brunetti‐Pierri   +2 more
wiley   +1 more source

Effects of nonsteroidal anti-inflammatory drugs on hearing

Turkish Archives of Otorhinolaryngology, 2012
Objectives: Non steroidal anti-inflammatory drugs (NSAID) use with high dose and long time for chronic inflammation. It was well known that these drugs have ototoxic effects.
Oğuz Güçlü, Ramazan Sargın, Kürşat Duman, Abdullah Ayçiçek, Fevzi Sefa Dereköy, Vural Kavuncu   +5 more
doaj   +1 more source

Effects of Perioperative Nonsteroidal Anti-inflammatory Drug Administration on Soft Tissue Healing: A Systematic Review of Clinical Outcomes After Sports Medicine Orthopaedic Surgery Procedures [PDF]

, 2019
This open-access article is published and distributed under the Creative Commons Attribution - NonCommercial - No Derivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits the noncommercial use, distribution, and reproduction
Vap, Alexander R., Constantinescu, David S., Moatshe, Gilbert, Campbell, Michael P.   +3 more
core   +1 more source

Dosing Interval Extension of Dupilumab in CRSwNP: Five‐Year Real World Outcomes

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent, often Type 2‐mediated inflammatory disease that markedly impairs quality of life. While dupilumab provides rapid improvement, there is limited evidence on long‐term outcomes beyond 2 years, and the clinical impact of dosing‐interval extension remains unclear.
Nicholas J. Campion, Dioni‐Pinelopi Petsiou, Florian C. Fally, Karina Berbalk, Noah F. Melamed, Aldine Tu, Christina Morgenstern, Fana Alem Kidane, Mohammed Zghaebi, Linda Liu, Minghao Pan, Tina J. Bartosik, Victoria Stanek, Katarina Gangl, Julia Eckl‐Dorna, Sven Schneider   +15 more
wiley   +1 more source

Clinical Management of Nonsteroidal Anti-inflammatory Drug Hypersensitivity

World Allergy Organization Journal, 2008
Hypersensitivity diseases caused by nonsteroidal anti-inflammatory agents are relatively common in the population. This article summarizes the present understanding on the various allergic and nonallergic clinical pictures produced through ...
Mario Sánchez-Borges, MD
doaj   +1 more source