Results 81 to 90 of about 75,006 (261)

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

Arthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf, Puja P. Khanna, Milan Petronijevic, Mamuka Lortkipanidze, Anand Patel, Kwabena Ayesu, Michael H. Pillinger, Atul Singhal, Joanna Sobierska, Jacquie Christie, Peter Traber, Rehan Azeem, Wesley DeHaan, Hugues Santin‐Janin, Bhavisha Desai, Alan Kivitz   +15 more
wiley   +1 more source

Acute Renal Failure and Nonsteroidal Anti-Inflammatory Drugs

Turkish Journal of Nephrology, 2019
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Tansu SAV
doaj  

Deep Immunophenotyping Reveals Distinct Immune Signatures in Axial Spondyloarthritis and Psoriatic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) are overlapping yet distinct conditions within the SpA spectrum. As divergent immunophenotypes may influence disease course and therapeutic response, we compared immune cell subsets, cytokine profiles, and inflammatory mediators.
Natalie Frede, Nils Craig‐Müller, Silke Kohrt, Marei‐Theresa Bott, Ulrich Salzer, Ana Cecilia Venhoff, Jens Thiel, Julia Frede, Reinhard E. Voll, Marta Rizzi, Raquel Lorenzetti, Nils Venhoff   +11 more
wiley   +1 more source

Afebrile vancomycin-induced delayed hypersensitivity suggestive of incomplete drug rash with eosinophilia and systemic symptoms syndrome: a case report

Journal of Medical Case Reports
Background Vancomycin-induced delayed hypersensitivity reactions are rare and typically accompanied by systemic symptoms such as fever, eosinophilia, and organ dysfunction, known as drug reaction with eosinophilia and systemic symptoms syndrome. However,
Chien-Hung Chou, Kun-Chuan Chang, Chi-Lan Kao, Kun-Jing Hong   +3 more
doaj   +1 more source

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

Arthritis &Rheumatology, Accepted Article.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week (W), double‐blind, placebo‐controlled, phase 3 POETYK PsA‐2 study
Philip J. Mease, Vinod Chandran, April W. Armstrong, Ricardo Blanco, Alexis Ogdie, Evan L. Siegel, Alice B. Gottlieb, Xiaofeng Zeng, Diamant Thaçi, Mitsumasa Kishimoto, Hendrik Schulze‐Koops, Alan Kivitz, Eva Dokoupilová, Akimichi Morita, Eric M. Ruderman, Michael Plewinski, Kejia Wang, Caroline Sardinas, Eleni Vritzali, John Vaile, Atul Deodhar   +20 more
wiley   +1 more source

Proximal Fibular Osteotomy: A Refined Surgical Technique for Medial Compartment Knee Osteoarthritis

Arthroscopy Techniques, EarlyView.
Abstract Proximal fibular osteotomy is a minimally invasive and cost‐effective option for medial compartment knee osteoarthritis. This refined technique, performed under spinal anesthesia using Henry's posterolateral approach, involves a small incision approximately 10 cm distal to the fibular head, careful dissection through the peroneus longus plane,
Mohammad Ayati Firoozabadi, Mohammad Rastegar, Pouya Tabatabaei Irani, Rahmatullah Azimi, Armin Akbarzadeh, Seyed Mohammad Javad Mortazavi   +5 more
wiley   +1 more source

Risk of stroke associated with nonsteroidal anti-inflammatory drugs

Vascular Health and Risk Management, 2014
Ki Park, Anthony A BavryDivision of Cardiovascular Medicine, University of Florida, Gainesville, FL, USAAbstract: Nonsteroidal anti-inflammatory drugs (NSAIDs), both cyclooxygenase (COX)-2-selective and nonselective agents, have been associated with the ...
Park K, Bavry AA
doaj  

Arthroscopic Radial Styloidectomy: An All‐Dorsal Two‐Portal Surgical Technique

Arthroscopy Techniques, EarlyView.
Abstract Radial‐sided wrist pain and impingement are recognized sources of persistent symptoms following 4‐corner fusion, often related to radioscaphoid contact and progressive degenerative changes. Radial styloidectomy has been described as a surgical option to address this pathology while preserving carpal stability.
Frank L. Vazquez, Anna L. Gorsky, Kier Blevins, Krishna N. Chopra, Nina Suh, Eric R. Wagner   +5 more
wiley   +1 more source

Non-Steroidal Anti Inflammatory Drugs and Gastrointestinal Toxicity

Apollo Medicine, 2010
Divij Mehta, DK Bhargava
doaj   +1 more source

Topical nonsteroidal anti-inflammatory drugs for management of osteoarthritis in long-term care patients

Therapeutics and Clinical Risk Management, 2011
Charles E Argoff1, F Michael Gloth2 1Albany Medical College and Comprehensive Pain Center, Albany Medical Center, Albany, NY, USA; 2Johns Hopkins University School of Medicine, Baltimore, MD, USA Abstract: Osteoarthritis is common in patients ≥65 ...
Argoff CE, Gloth FM
doaj