Results 91 to 100 of about 56,005 (221)

Hemipteran vectors of stylet‐borne plant viruses: Aphids lead the charge

open access: yesInsect Science, EarlyView.
Among all sap‐feeding hemipterans, aphids stand out by far as the most important vectors of noncirculative plant viruses. Compared to whiteflies and mealybugs, aphids’ highly specialized stylet anatomy and distinct feeding behaviors contribute, together with other features of their biology, to their remarkable efficiency in transmitting stylet‐borne ...
Yu Fu, Stefano Colella, Marilyne Uzest
wiley   +1 more source

A link between increased temperature and avian body condition in a logged tropical forest

open access: yesConservation Biology, EarlyView.
Abstract The combined effects of anthropogenic disturbances, such as logging and climate change, remain poorly understood; yet, they are the main threats to tropical biodiversity. Most tropical African countries lack long‐term climate data, so climate impacts on biodiversity cannot be assessed.
Moreen Uwimbabazi   +7 more
wiley   +1 more source

Development of a Noninfectious Japanese Encephalitis Virus Replicon for Antiviral Drug Screening and Gene Function Studies

open access: yesViruses
Viral replicons are efficient tools to understand the mechanisms of viral replication and screen antiviral drugs. In this study, a viral-cDNA-based replicon of Japanese encephalitis virus (JEV), which is the causative agent of Japanese encephalitis, was ...
Yang Yang   +13 more
doaj   +1 more source

Mutagenesis of the conserved 51-nucleotide region of Sindbis virus [PDF]

open access: yes, 1990
We have constructed 25 site-specific mutations in a domain of 51 nucleotides in Sindbis virus that is highly conserved among all alphaviruses sequenced to date.
Niesters, Hubert G. M.   +1 more
core  

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. [PDF]

open access: yes, 2010
Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection.
Carpentier, Arnaud   +7 more
core   +1 more source

Diagnosis and management of equine metabolic syndrome

open access: yesEquine Veterinary Education, EarlyView.
Summary Equine metabolic syndrome (EMS) is a prevalent endocrine disorder that increases the risk of hyperinsulinaemia‐associated laminitis (HAL), the most common and clinically significant form of laminitis. The central pathological feature of EMS is insulin dysregulation (ID), which encompasses basal or postprandial hyperinsulinaemia and tissue ...
F. R. Bertin
wiley   +1 more source

Rotavirus NSP2: A Master Orchestrator of Early Viral Particle Assembly

open access: yesViruses
Rotaviruses (RVs) are 11-segmented, double-stranded (ds) RNA viruses and important causes of acute gastroenteritis in humans and other animal species.
Sarah L. Nichols   +3 more
doaj   +1 more source

Conformational Isomerization Involving Conserved Proline Residues Modulates Oligomerization of the NS1 Interferon Response Inhibitor from the Syncytial Respiratory Virus [PDF]

open access: yes, 2019
Interferon response suppression by the respiratory syncytial virus relies on two unique nonstructural proteins, NS1 and NS2, that interact with cellular partners through high-order complexes.
Alonso, Leonardo Gabriel   +9 more
core   +1 more source

Long‐Term Salt Exposure Reprograms the Nicotiana tabacum BY‐2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz   +8 more
wiley   +1 more source

Host immune response to cytomegalovirus [PDF]

open access: yes, 1987
To confirm that immediate-early (IE) genes of murine cytomegalovirus (MCMV) give rise to antigens recognized by specific cytolytic T lymphocytes (CTL), a 10.8-kilobase fragment of MCMV DNA which is abundantly transcribed at IE times was transfected into ...
Keil, Günther M.   +3 more
core  

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