Results 41 to 50 of about 2,917 (175)
Nontypeable Haemophilus influenzae genetic islands associated with chronic pulmonary infection. [PDF]
PLoS ONE, 2012 BackgroundHaemophilus influenzae (Hi) colonizes the human respiratory tract and is an important pathogen associated with chronic obstructive pulmonary disease (COPD).
Lixin Zhang +10 more
doaj +1 more source
Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease
Food Science &Nutrition, Volume 14, Issue 7, July 2026.This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley +1 more source
Frontiers in Microbiology, 2014 Nontypeable Haemophilus influenzae (NTHi) and Haemophilus haemolyticus are closely related bacteria that reside in the upper respiratory tract. NTHi is associated with respiratory tract infections that frequently result in antibiotic prescription whilst ...
Janessa ePickering +4 more
doaj +1 more source
The DmsABC Sulfoxide Reductase Supports Virulence in Non-typeable Haemophilus influenzae
Frontiers in Microbiology, 2021 Although molybdenum-containing enzymes are well-established as having a key role in bacterial respiration, it is increasingly recognized that some may also support bacterial virulence.
Rabeb Dhouib +8 more
doaj +1 more source
VapC-1 of Nontypeable Haemophilus influenzae Is a Ribonuclease [PDF]
Journal of Bacteriology, 2007 ABSTRACT Nontypeable Haemophilus influenzae (NTHi) organisms are obligate parasites of the human upper respiratory tract that can exist as commensals or pathogens. Toxin-antitoxin (TA) loci are highly conserved gene pairs that encode both a toxin and antitoxin moiety.
Daines, Dayle A +2 more
openaire +3 more sources
Acetate‐Linked Energy Metabolism as a Determinant of Early Haemophilus influenzae Infection Fitness
MicrobiologyOpen, Volume 15, Issue 3, June 2026.The Pta–AckA pathway is critical for Haemophilus influenzae energy generation, metabolic homeostasis, stress resistance, and intracellular colonization, highlighting its potential as a target for management of H. influenzae infections.
Marufa Nasreen +8 more
wiley +1 more source
Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies
ChemBioChem, Volume 27, Issue 9, 14 May 2026.This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci +5 more
wiley +1 more source
Epithelial immune activation and intracellular invasion by non-typeable Haemophilus influenzae
Frontiers in Cellular and Infection Microbiology, 2023 Type-2 low asthma affects 30-50% of people with severe asthma and includes a phenotype characterized by sputum neutrophilia and resistance to corticosteroids. Airways inflammation in type-2 low asthma or COPD is potentially driven by persistent bacterial
Mary A. Brown +6 more
doaj +1 more source
Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments
APMIS, Volume 134, Issue 3, March 2026.ABSTRACT Biofilms formed by mycobacteria, particularly Mycobacterium tuberculosis (Mtb), represent a major challenge in tuberculosis (TB) treatment due to their highly organized structure and their capacity to induce phenotypic drug tolerance. These three‐dimensional bacterial aggregates are embedded in a self‐produced extracellular matrix that ...
Lourdes Serrano Garcia +3 more
wiley +1 more source
Epidemiology of Invasive Haemophilus influenzae Disease, Europe, 2007–2014
Emerging Infectious Diseases, 2017 We describe the epidemiology of invasive Haemophilus influenzae disease during 2007–2014 in 12 European countries and assess overall H. influenzae disease trends by serotype and patient age. Mean annual notification rate was 0.6 cases/100,000 population,
Robert Whittaker +5 more
doaj +1 more source