Results 51 to 60 of about 2,917 (175)

Etiology of pediatric lower respiratory tract infections in South Korea

Human Vaccines & Immunotherapeutics, 2022
Lower respiratory tract infections (LRTIs) are an important cause of death and bacterial pneumonia is one of the most common causes of mortality in South Korea, but there is little data evaluating the epidemiology of pediatric LRTI in primary care ...
Jun Won Yang, Dae Sun Jo
doaj   +1 more source

Chorioamnionitis in the Second Trimester Secondary to Multidrug‐Resistant Haemophilus influenzae Infection

Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
Purpose Nontypeable Haemophilus influenzae (NTHi) is an emerging perinatal pathogen linked to chorioamnionitis, preterm birth, and early pregnancy loss. This case report describes the presentation, microbiologic findings, and management of second‐trimester NTHi‐associated chorioamnionitis, emphasizing diagnostic challenges and antimicrobial ...
Karen S. Carlson, Morgan Baker Korthals, Priya Gusain   +2 more
wiley   +1 more source

Biofilm formation by nontypeable Haemophilus influenzae: strain variability, outer membrane antigen expression and role of pili

BMC Microbiology, 2002
Background Nontypeable Haemophilus influenzae is an important cause of otitis media in children and lower respiratory tract infection in adults with chronic obstructive pulmonary disease (COPD).
Murphy Timothy F, Kirkham Charmaine
doaj   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, Volume 12, Issue 32, August 28, 2025.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Platelet Activating Factor Receptor Activation Improves siRNA Uptake and RNAi Responses in Well-differentiated Airway Epithelia

Molecular Therapy: Nucleic Acids, 2014
Well-differentiated human airway epithelia present formidable barriers to efficient siRNA delivery. We previously reported that treatment of airway epithelia with specific small molecules improves oligonucleotide uptake and facilitates RNAi responses ...
Sateesh Krishnamurthy, Mark A Behlke, Michael A Apicella, Paul B McCray, Jr, Beverly L Davidson   +4 more
doaj   +1 more source

Beyond the Toll‐Like Receptor 4. Structure‐Dependent Lipopolysaccharide Recognition Systems: How far are we?

ChemMedChem, Volume 20, Issue 6, March 15, 2025.
This review goes beyond the famous MD‐2/TLR4‐mediated recognition of LPS, pointing the attention on other immune detection systems and their impact on human physiology and pathology. Understanding these additional pathways is key for the development of pharmacologically active molecules to modulate the immune response and to conceive new strategies to ...
Stefania De Chiara, Luca De Simone Carone, Roberta Cirella, Emanuela Andretta, Alba Silipo, Antonio Molinaro, Marcello Mercogliano, Flaviana Di Lorenzo   +7 more
wiley   +1 more source

Nontypeable Haemophilus influenzae biofilms: role in chronic airway infections

Frontiers in Cellular and Infection Microbiology, 2012
Like many pathogens inhabiting mucosal surfaces, nontypeable Haemophilus influenzae (NTHi) forms multicellular biofilm communities both in vitro and in various infection models.
W Edward Swords
doaj   +1 more source

HrrF is the Fur-regulated small RNA in nontypeable Haemophilus influenzae. [PDF]

PLoS ONE, 2014
Nontypeable Haemophilus influenzae (NTHi) are Gram-negative commensal bacteria that reside in the nasopharynx. NTHi can also cause multiple upper and lower respiratory tract diseases that include sinusitis, conjunctivitis, bronchitis, and otitis media ...
Estevan A Santana, Alistair Harrison, Xinjun Zhang, Beth D Baker, Benjamin J Kelly, Peter White, Yunlong Liu, Robert S Munson   +7 more
doaj   +1 more source

Immunometabolism of Liver Xenotransplantation and Prospective Solutions

Advanced Science, Volume 12, Issue 9, March 6, 2025.
After xenotransplantation, pig livers will replace those of human patients to maintain the stability of metabolism and immune system. The incompatibility of immunometabolism between humans and pigs induces rejection, inflammation, coagulation dysfunction, and liver failure. The profile of immunometabolism pre‐transplantation and post‐transplantation is
Shoulong Deng, Yi Zhang, Shasha Shen, Chongyang Li, Chuan Qin   +4 more
wiley   +1 more source

Exploring the Potential of Nanogels: From Drug Carriers to Radiopharmaceutical Agents

Advanced Healthcare Materials, Volume 13, Issue 1, January 4, 2024.
Nanogels are universally applicable materials mainly being used for drug delivery systems, tissue engineering, and sensor development. More recently, radiolabeled nanogels have also been reported. This class of compounds holds an enormous potential for theranostic applications.
Manja Kubeil, Yota Suzuki, Maria Antonietta Casulli, Rozy Kamal, Takeshi Hashimoto, Michael Bachmann, Takashi Hayashita, Holger Stephan   +7 more
wiley   +1 more source