Results 31 to 40 of about 50,750 (233)

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

The Contributing Factors of Nonunion Bone Fractures: A Brief Review

Journal of Orthopedic and Spine Trauma, 2022
The skeletal system has a high healing capacity. A nonunion fracture occurs when the natural course of bone healing is impaired. Numerous local and systemic factors participate in the development of a nonunion fracture.
Hamidreza Zafari, Seyed Arman Moein, Mohamadreza Razzaghof, SM Javad Mortazavi   +3 more
doaj   +1 more source

Injectable Porous Microspheres Loaded With Biomimetic Preconditioned Bone Marrow Mesenchymal Stem Cell‐Derived Exosomes for Vascularized Bone Regeneration

Advanced Science, EarlyView.
Schematic illustration of injectable PDA‐modified GelMA microspheres loaded with BioPre‐Exos for vascularized bone regeneration. ABSTRACT Critical‐sized bone defects remain a highly challenging clinical problem due to insufficient intrinsic self‐healing capacity.
Lijun Li, Hao Zhang, Lingtong Sun, Yingfeng Su, Yang Xu, Jian Huang, Jingchao Wen, Jinjin Zhu, Jianjun Ma, Wenbin Xu   +9 more
wiley   +1 more source

Labor Market Outcomes of Deregulation in Telecommunications Services [PDF]

, 1998
[Excerpt] This paper examines the labor market outcomes of deregulation in the telecommunications industry, focusing specifically on changes in union density, real wages, wage inequality, and employment levels.
Batt, Rosemary, Strausser, Michael
core   +2 more sources

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

The Anatomical Record, EarlyView.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille, Kyla Beguesse, Ewan Wolff, Clemens Zinner, Patrick Asbach, François Clarac, Florian Witzmann   +6 more
wiley   +1 more source

The Risk Factors of Patients with Cruris Fracture Nonunion in Dr. Mohamad Soewandhie Hospital in 2021-2022: A Case-Control Study

Journal Orthopaedi and Traumatology Surabaya
Background: The crural region is highly susceptible to injury in Indonesia, with fractures being a common occurrence. If not properly treated, these fractures can lead to complications such as nonunion. To investigate the risk factors for nonunion cruris
Regina Clarissa, Bimo Sasono, Ni Njoman Juliasih   +2 more
doaj   +1 more source

Telecommunications 2000 Strategy, HR Practices & Performance [PDF]

, 2000
This report constitutes the first benchmarking survey of business and human resource practices among a nationally representative sample of workplaces in the broadly defined telecommunications industry that includes wireline, wireless, cable, and internet
Batt, Rosemary, Colvin, Alexander, Katz, Harry C., Keefe, Jeffrey   +3 more
core   +1 more source

Medium to long-term outcome of thoracoscapular arthrodesis with screw fixation for facioscapulohumeral muscular dystrophy [PDF]

, 2013
Background: Shoulder girdle muscle weakness is the most constant feature of facioscapulohumeral muscular dystrophy and leads to scapular winging. Mechanical fixation of the scapula to the thoracic wall provides a stable fulcrum on which the deltoid ...
Atoun, Ehud, Copeland, Stephen, Levy, Ofer, Narvani, Ali, Sforza, Giuseppe, Van Tongel, Alexander   +5 more
core   +2 more sources

Modified arthroscopic suture‐button Latarjet procedure for recurrent anterior shoulder instability: 9‐Year minimum follow‐up

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purposes To evaluate the efficacy of the modified arthroscopic suture‐button (MASB) Latarjet procedure with at least 9 years of follow‐up and remodelling of the coracoid grafts (CGs). Methods Patients who underwent the MASB Latarjet procedure between February 2013 and February 2016 were retrospectively reviewed.
Wei Lu, Daqiang Liang, Shengwu Yang, Yan Liu, Guoqing Cui, Chunwu Zhang, Shuguang Gao, Zhenhan Deng   +7 more
wiley   +1 more source