Retraction notice to “Noopept; a nootropic dipeptide, modulates persistent inflammation by effecting spinal microglia dependent Brain Derived Neurotropic Factor (BDNF) and pro-BDNF expression throughout apoptotic process” [Heliyon (2021) e06219] [PDF]
Heliyon, 2021 Mona Taghizadeh +8 more
doaj +2 more sources
Study of excipients influence on the noopept releasing from the nasal dosage form
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019 The development of medicines for fast delivery is the actual direction of modern pharmacy. In this connection, the nasal route of drug administration is perspective and has some advantages. The greater permeability of nasal mucosa with large surface area
B. S. Burlaka +2 more
doaj +4 more sources
Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. [PDF]
J Biomed Sci, 2014 Ostrovskaya RU +7 more
europepmc +2 more sources
Intranasal Administration of Forskolin and Noopept Reverses Parkinsonian Pathology in PINK1 Knockout Rats. [PDF]
Int J Mol Sci, 2022 Parkinson’s Disease (PD) is a brain-degenerative disorder characterized by a progressive loss of midbrain dopamine neurons. Current standard-of-care includes oral administration of Levodopa to address motor symptoms, but this treatment is not disease-modifying.
Dagda RK +4 more
europepmc +3 more sources
The use of HPLC-Q-TOF-MS for comprehensive screening of drugs and psychoactive substances in hair samples and several "legal highs" products. [PDF]
Monatsh Chem, 2016 Aszyk J, Kot-Wasik A.
europepmc +2 more sources
Molecular Mechanism Underlying the Action of Substituted Pro-Gly Dipeptide Noopept. [PDF]
Acta Naturae, 2016 This study was performed in order to reveal the effect of Noopept (ethyl ester of N-phenylacetyl-Lprolylglycine, GVS-111) on the DNA-binding activity of transcriptional factors (TF) in HEK293 cells transiently transfected with luciferase reporter constructs containing sequences for CREB, NFAT, NF-B, p53, STAT1, GAS, VDR, HSF1, and HIF-1. Noopept (10 M)
Vakhitova YV +5 more
europepmc +5 more sources
Екстракти кріоконсервованих фрагментів органів свиней та поросят як компонент відновної медицини [PDF]
, 2017 Досліджено пептидний склад екстрактів кріоконсервованих фрагментів органів свиней та поросят і їх біологічну активність при експериментальних патологічних станах. Показано, що вихід пептидів у розчин більший з кріоконсервованих фрагментів органів свиней
Гальченко, С.Є. +1 more
core +2 more sources
Effects of pharmacological drugs on synaptic activity of hippocampus
Анналы клинической и экспериментальной неврологии, 2017 The search for physiologically active drugs with precognitive action and the study of mechanisms of their influence on the brain represent important tasks of neurobiology and neuropharmacology.
V. G. Skrebitsky +3 more
doaj +1 more source
Specific Aspects of Changes in Cognitive Function in Cerebral Circulatory Disorders [PDF]
, 2022 Violation of higher brain functions is one of the most frequent and disadaptive complications of cerebrovascular diseases. Cognitive impairments, especially pronounced ones, can lead to significant restrictions in work, social life, and self-care of ...
Jalolovich, Tulayev Mirzohid
core +1 more source
Theragnostics of TRK-targeting agents (trackins): a challenge that promises reward [PDF]
, 2022 Therminologically, theragnostics combines therapeutics and diagnostics. Life at cellular and molecular level is a binary event (e.g., phosphorylation-dephosphorylation of proteins, methylation-demethylations of DNA and acetylation-deacetylation of ...
Aloe, Luigi +8 more
core +2 more sources