4-Methoxy-α-PVP: in silico prediction, metabolic stability, and metabolite identification by human hepatocyte incubation and high-resolution mass spectrometry [PDF]
, 2015 Novel psychoactive substances are continuously developed to circumvent legislative and regulatory efforts. A new synthetic cathinone, 4-methoxy-α-PVP, was identified for the first time in illegal products; however, the metabolism of this compound is not ...
Ariane Wohlfarth +5 more
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Проявление патогномоничных признаков при моделировании сахарного диабета стрептозотоцином у мышей BALB/c [PDF]
, 2023 Relevance. Diabetes mellitus is a widespread, socially significant disease. In this regard, it is important to obtain an experimental model that precedes subsequent experiments on pharmacological screening and/or study of the mechanism of action of ...
A. A. Lisitsyn +11 more
core +4 more sources
Pharmacological Investigations of the Dissociative ‘Legal Highs’ Diphenidine, Methoxphenidine and Analogues [PDF]
, 2016 1,2-Diarylethylamines including lanicemine, lefetamine, and remacemide have clinical relevance in a range of therapeutic areas including pain management, epilepsy, neurodegenerative disease and depression.
A Helander +56 more
core +6 more sources
Фармакокинетика и Фармакодинамика, 2018 Resume. The paper presents literature data about the interspecific differences of the pharmacokinetics of peptide drugs and the results of our own studies on the inter-specific features of the pharmacokinetics of the 3 modified analogues of endogenous ...
V. P. Zherdev +5 more
doaj +1 more source
Possibilities of pharmacologic correction of cognitive disorders in conditions of experimental equivalent of multiple sclerosis. [PDF]
, 2015 A comparative analysis of the impact of citicoline, α-lipoic acid, nicergoline, donepezil and colloidal solution of nano-silver (CSNS) on the processes of learning and consolidation of memorable track in the test of the conditional reaction of passive ...
A. A. Nefyodov, V. Io. Mamchur
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Biotechnic & Histochemistry, 2023 Diabetes mellitus (DM) is a chronic disease at all ages including childhood and puberty. Failure to treat DM can cause retinopathy, nephropathy and neuropathy. Endocrine and metabolic changes during the pubertal period complicate management of DM. Noopept is a cognitive enhancer that exhibits antidiabetic properties.
Perihan Gurbuz +3 more
openaire +3 more sources
Влияние ноопепта на поведение мышей разных линий в TST-тесте [PDF]
, 2008 НООПЕП
Кравченко, Е. В. +1 more
core
The relationship between the content of the potential psychopharmacological agent cyclo-L-prolylglycine in the brain of experimental animals and its antihypoxic effect [PDF]
, 2020 In the study of strutural and intracellular distribution of cyclo-t-prolylglycine (CPG) in brain rats in experiments on mongrel white male rats, it was found that CPG determined more in the hippocampus and cerebral cortex with predominant localization in
K. N. Kolyasnikova +2 more
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Влияние ноопепта на показатели угашения (габитуации) у нелинейных мышей и у мышей линии BALB/C [PDF]
, 2007 НООПЕПТТРЕВОЖНОСТИ ШКАЛА ...
Гудашева, Т. А. +3 more
core
From Antitubulins to Trackins [PDF]
, 2017 Microtubules (MT) are dynamically instable, assembling and disassembling structures of the cell. Tubulin, the major building protein of MT, is a heterodimer consisting of α and ẞ subunits.
Aloe, Luigi +9 more
core +2 more sources