Results 21 to 30 of about 196 (129)

Potential uses of omberacetam (Noopept©) in the early prevention and management of cognitive impairment

Российский журнал гериатрической медицины
BACKGROUND. Cognitive impairment represents a growing global health challenge due to population aging and the increasing prevalence of chronic non-communicable diseases.
O. N. Tkacheva, O. M. Drapkina, S. A. Berns, E. A. Mkhitaryan, M. A. Cherdak, N. N. Koberskaya, I. V. Kolykhalov, O. S. Zaitsev, S. N. Mosolov, S. V. Seredenin, Yu. V. Vakhitova, I. D. Strazhesko, M. V. Metlina   +12 more
doaj   +2 more sources

Research progress on intranasal treatment for Parkinson's disease. [PDF]

Neuroprotection
Intranasal treatment: A promising choice for Parkinson's disease (PD). Abstract Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder globally, significantly affecting the quality of life of affected individuals. Systemic drug delivery to the brain is inefficient because of first‐pass metabolism, the blood‐brain barrier (BBB),
Wen P, Ren C.
europepmc   +2 more sources

Effects Of Noopept On Eye And Kidney In Prepubertal Rats With Streptozotocin-Induced Diabetes

, 2018
Öz bulunamadı.
Gurbuz, Perihan, Duzova, Halil, Gul, Cemile Ceren, Taslidere, Asli Cetin   +3 more
openaire   +3 more sources

Morpho-functional parameters of neurons in the sensorimotor cortex and neuroapoptosis under conditions of an induced experimental allergic encephalomyelitis in rats and a course of intranasal gel administration containing n-phenylacetyl-l-prolylglycine (N

Journal of Education, Health and Sport, 2021
Purpose. The aim of the research is to evaluate a neuroprotective effect of the nasal dosage form containing Noopept (n-phenylacetyl-l-prolylglycine ethyl ester) by the degree of influence on morphofunctional parameters of neurons in the sensorimotor ...
B. S. Burlaka, I. F. Bielenichev, S. G. Nosach, A. A. Nefedov   +3 more
doaj   +1 more source

Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. [PDF]

J Biomed Sci, 2014
Ostrovskaya RU, Vakhitova YV, Kuzmina USh, Salimgareeva MKh, Zainullina LF, Gudasheva TA, Vakhitov VA, Seredenin SB.   +7 more
europepmc   +2 more sources

Effects of pharmacological drugs on synaptic activity of hippocampus

Анналы клинической и экспериментальной неврологии, 2017
The search for physiologically active drugs with precognitive action and the study of mechanisms of their influence on the brain represent important tasks of neurobiology and neuropharmacology.
V. G. Skrebitsky, N. A. Kapay, V. I. Derevyagin, R. V. Kondratenko   +3 more
doaj   +1 more source

ANALYSIS OF ATTRIBUTION OF NOOPEPT TO SUBSTRATES AND MODULATORS OF FUNCTIONAL ACTIVITY OF ABCB1-PROTEIN IN IN VIVO EXPERIMENT

, 2017
In the article the influence of nootropic drug Noopept (N-phenyl-acetyl-L-prolylglycine ethyl ester) on the functional activity of ABCB1-protein is analyzed and attribution of this drug to the transport protein substrates is studied on male Chinchilla ...
A V. Shchulkin, N M. Popova, E N. Yakusheva, I V. Chernykh, M V. Gatsanoga   +4 more
core   +1 more source

A State‐of‐the‐Art Appraisal of Nanomaterials in Microneedles in the Delivery of Therapeutics and Vaccines

Advanced NanoBiomed Research, Volume 5, Issue 3, March 2025.
Nanomaterial‐integrated microneedles revolutionize transdermal delivery, enabling targeted and controlled administration of therapeutics and vaccines. This review explores advancements in design, manufacturing, and applications, emphasizing enhanced drug stability, bioavailability, and patient adherence. Key preclinical and clinical findings as well as
Bwalya Angel Witika, Aaron Hutton, Pedzisai A. Makoni, Ryan F. Donnelly   +3 more
wiley   +1 more source

Effects of nootropics on the EEG in conscious rats and their modification by glutamatergic inhibitors

, 2011
To study the effects of acute and repeated injections of nootropics and to learn how glutamate receptors might be involved in their mediation, the frequency spectra of cortical and hippocampal electroencephalogram (EEG) were analyzed in non-narcotized ...
Sengpiel, Frank, Vasily Vorobyov, Georgy Kovalev, Frank Sengpiel, Vladimir Kaptsov, Vorobyov, Vasily, Kaptsov, Vladimir, Kovalev, Georgy   +7 more
core   +1 more source

Сравнительная активность ноопепта и пирацетама на модели интрацеребральной посттравматической гематомы

, 2008
Us KS, Kraineva VA, Galaeva IP, Garibova TL, Ostrovskaya RU, Voronina TA. [The comparative effect of noopept and piracetam in rats with intracerebral posttraumatic hematoma (hemmorrhagic stroke)]. Psychopharmacol Biol Narcol.
Р. У. Островская; Zakusov Institute of Pharmacology RAMS; 8, Baltiiskaya st., Moscow, 125315, Russia, Т. А. Воронина; Zakusov Institute of Pharmacology RAMS; 8, Baltiiskaya st., Moscow, 125315, Russia, К. С. Ус; Zakusov Institute of Pharmacology RAMS; 8, Baltiiskaya st., Moscow, 125315, Russia, В. А. Крайнева; Zakusov Institute of Pharmacology RAMS; 8, Baltiiskaya st., Moscow, 125315, Russia, Т. Л. Гарибова; Zakusov Institute of Pharmacology RAMS; 8, Baltiiskaya st., Moscow, 125315, Russia, И. П. Галаева; Zakusov Institute of Pharmacology RAMS; 8, Baltiiskaya st., Moscow, 125315, Russia   +5 more
core   +1 more source