Results 1 to 10 of about 236,386 (163)
PLoS ONE, 2022 Dopaminergic neuron degeneration in the midbrain plays a pivotal role in motor symptoms associated with Parkinson’s disease. However, non-motor symptoms of Parkinson’s disease and post-mortem histopathology confirm dysfunction in other brain areas ...
Predrag Jovanovic +7 more
doaj +2 more sources
Frontiers in Medicine, 2022 BackgroundThe optimal management of hypotensive patients during norepinephrine weaning is unclear. The primary study aim was to assess the ability of preload dependence to predict hypotension following norepinephrine weaning.
Stefan Andrei +8 more
doaj +1 more source
Norepinephrine use in cardiogenic shock patients is associated with increased 30 day mortality
ESC Heart Failure, 2022 Aims Norepinephrine is recommended as a first‐line vasopressor agent in the haemodynamic stabilization of cardiogenic shock. The survival benefit of norepinephrine therapy has not been demonstrated in clinical practice, however.
Xin Lu +8 more
doaj +1 more source
Dose-related effects of norepinephrine on early-stage endotoxemic shock in a swine model
Journal of Intensive Medicine, 2023 Background: The benefits of early use of norepinephrine in endotoxemic shock remain unknown. We aimed to elucidate the effects of different doses of norepinephrine in early-stage endotoxemic shock using a clinically relevant large animal model.
Hui Xiang +7 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Purpose: The relative potency of norepinephrine and phenylephrine given as boluses to treat hypotension during spinal anesthesia for cesarean delivery has been reported but few data are available for infusions.
Jing Qian +13 more
doaj +1 more source
BMC Anesthesiology, 2020 Background Data on the best norepinephrine bolus dose for management of hypotension are limited. The aim of this study was to compare the efficacy and safety of two norepinephrine bolus doses in the rescue management of maternal hypotension during ...
Yasmin S. Hassabelnaby +11 more
doaj +1 more source
Effect of methylphenidate treatment during adolescence on norepinephrine transporter function in orbitofrontal cortex in a rat model of attention deficit hyperactivity disorder [PDF]
, 2010 Attention deficit hyperactivity disorder (ADHD) is associated with hypofunctional medial prefrontal cortex (mPFC) and orbitofrontal cortex (OFC). Methylphenidate (MPH) remediates ADHD, in part, by inhibiting the norepinephrine transporter (NET). MPH also
Somkuwar, Sucharita S. +2 more
core +4 more sources
Chinese Medical Journal, 2021 . Background:. Norepinephrine infusion decreases hypotension after spinal anesthesia during cesarean section. This study aimed to compare the efficacy of norepinephrine infusion and ephedrine bolus against post-spinal hypotension in parturients. Methods:.
Qian-Qian Fan +11 more
doaj +1 more source
Mobilisation of critically ill patients receiving norepinephrine: a retrospective cohort study
Critical Care, 2022 Background Mobilisation and exercise intervention in general are safe and feasible in critically ill patients. For patients requiring catecholamines, however, doses of norepinephrine safe for mobilisation in the intensive care unit (ICU) are not defined.
Maximilian Lindholz +12 more
doaj +1 more source
eLife, 2021 We examined the relationships between activity in the locus coeruleus (LC), activity in the primary somatosensory cortex (S1), and pupil diameter in mice performing a tactile detection task.
Hongdian Yang +3 more
doaj +1 more source