Results 1 to 10 of about 242,932 (337)

Comparison between norepinephrine plus epinephrine and norepinephrine plus vasopressin after return of spontaneous circulation in patients with out-of-hospital cardiac arrest [PDF]

Scientific Reports
There is insufficient evidence regarding the use of second-line vasopressors following norepinephrine administration in the post-resuscitation management of patients with out-of-hospital cardiac arrest (OHCA).
Sejoong Ahn, Bo-Yeong Jin, Sukyo Lee, Jong-Hak Park, Hanjin Cho, Sungwoo Moon, Korean Cardiac Arrest Research Consortium (KoCARC) Investigators   +6 more
doaj   +2 more sources

Sustained chemogenetic activation of locus coeruleus norepinephrine neurons promotes dopaminergic neuron survival in synucleinopathy

PLoS ONE, 2022
Dopaminergic neuron degeneration in the midbrain plays a pivotal role in motor symptoms associated with Parkinson’s disease. However, non-motor symptoms of Parkinson’s disease and post-mortem histopathology confirm dysfunction in other brain areas ...
Predrag Jovanovic, Yidan Wang, Jean-Philippe Vit, Edward Novinbakht, Nancy Morones, Elliot Hogg, Michele Tagliati, Celine E. Riera   +7 more
doaj   +2 more sources

Arterial Hypotension Following Norepinephrine Decrease in Septic Shock Patients Is Not Related to Preload Dependence: A Prospective, Observational Cohort Study

Frontiers in Medicine, 2022
BackgroundThe optimal management of hypotensive patients during norepinephrine weaning is unclear. The primary study aim was to assess the ability of preload dependence to predict hypotension following norepinephrine weaning.
Stefan Andrei, Stefan Andrei, Maxime Nguyen, Maxime Nguyen, Osama Abou-Arab, Belaid Bouhemad, Belaid Bouhemad, Pierre-Grégoire Guinot, Pierre-Grégoire Guinot   +8 more
doaj   +1 more source

Evaluating intraoperative norepinephrine versus fresh frozen plasma in patients undergoing cytoreductive surgery and HIPEC to reduce renal insult

Egyptian Journal of Anaesthesia, 2022
Objective This study aims to compare the efficacy of intraoperative norepinephrine infusion versus plasma in reducing renal insult during cytoreductive surgeries.Methods Sixty patients (ASA I–III) of both genders were included in the study. Plasma group:
Mohamed Adly, Mohamed Shalaby, Mohamed H Zedan, Walaa Y Elsabeeny   +3 more
doaj   +1 more source

Norepinephrine use in cardiogenic shock patients is associated with increased 30 day mortality

ESC Heart Failure, 2022
Aims Norepinephrine is recommended as a first‐line vasopressor agent in the haemodynamic stabilization of cardiogenic shock. The survival benefit of norepinephrine therapy has not been demonstrated in clinical practice, however.
Xin Lu, Xue Wang, Yanxia Gao, Joseph Harold Walline, Shiyuan Yu, Zengzheng Ge, Mubing Qin, Huadong Zhu, Yi Li   +8 more
doaj   +1 more source

Determination of the Relative Potency of Norepinephrine and Phenylephrine Given as Infusions for Preventing Hypotension During Combined Spinal-Epidural Anesthesia for Cesarean Delivery: A Randomized Up-And-Down Sequential Allocation Study

Frontiers in Pharmacology, 2022
Purpose: The relative potency of norepinephrine and phenylephrine given as boluses to treat hypotension during spinal anesthesia for cesarean delivery has been reported but few data are available for infusions.
Jing Qian, Jing Qian, Yan-Ping Zhao, Yan-Ping Zhao, Jia-Li Deng, Jia-Li Deng, Li-Zhong Wang, Li-Zhong Wang, Fei Xiao, Fei Xiao, Bei Shen, Bei Shen, Han-Qing Yao, Han-Qing Yao   +13 more
doaj   +1 more source

Comparison of two Norepinephrine rescue bolus for Management of Post-spinal Hypotension during Cesarean Delivery: a randomized controlled trial

BMC Anesthesiology, 2020
Background Data on the best norepinephrine bolus dose for management of hypotension are limited. The aim of this study was to compare the efficacy and safety of two norepinephrine bolus doses in the rescue management of maternal hypotension during ...
Yasmin S. Hassabelnaby, Ahmed M. Hasanin, Nada Adly, Maha M. A. Mostafa, Sherin Refaat, Eman Fouad, Mohamed Elsonbaty, Hazem A. Hussein, Mohamed Mahmoud, Yaser M. Abdelwahab, Ahmed Elsakka, Sarah M. Amin   +11 more
doaj   +1 more source

Effect of methylphenidate treatment during adolescence on norepinephrine transporter function in orbitofrontal cortex in a rat model of attention deficit hyperactivity disorder [PDF]

, 2010
Attention deficit hyperactivity disorder (ADHD) is associated with hypofunctional medial prefrontal cortex (mPFC) and orbitofrontal cortex (OFC). Methylphenidate (MPH) remediates ADHD, in part, by inhibiting the norepinephrine transporter (NET). MPH also
Somkuwar, Sucharita S., Kantak, Kathleen M., Dwoskin, Linda P.   +2 more
core   +4 more sources

Comparison of two vasopressor protocols for preventing hypotension post-spinal anesthesia during cesarean section: a randomized controlled trial

Chinese Medical Journal, 2021
. Background:. Norepinephrine infusion decreases hypotension after spinal anesthesia during cesarean section. This study aimed to compare the efficacy of norepinephrine infusion and ephedrine bolus against post-spinal hypotension in parturients. Methods:.
Qian-Qian Fan, Yong-Hui Wang, Jing-Wen Fu, Hai-Long Dong, Man-Ping Yang, Duo-Duo Liu, Xiao-Fan Jiang, Zhi-Xin Wu, Li-Ze Xiong, Zhi-Hong Lu, Yan-Jie Yin, Xiu-Yuan Hao   +11 more
doaj   +1 more source

Mobilisation of critically ill patients receiving norepinephrine: a retrospective cohort study

Critical Care, 2022
Background Mobilisation and exercise intervention in general are safe and feasible in critically ill patients. For patients requiring catecholamines, however, doses of norepinephrine safe for mobilisation in the intensive care unit (ICU) are not defined.
Maximilian Lindholz, Clara M. Schellenberg, Julius J. Grunow, Simone Kagerbauer, Annette Milnik, Daniel Zickler, Stefan Angermair, Anett Reißhauer, Martin Witzenrath, Mario Menk, Sebastian Boie, Felix Balzer, Stefan J. Schaller   +12 more
doaj   +1 more source