Norepinephrine Involvment in Penile Detumescence [PDF]
Journal of Urology, 1990 Adrenergic neurotransmission was studied in dogs. Blood samples for catecholamine assay were collected from the flaccid penis, the erect penis after cavernous nerve stimulation and during detumescence induced by sympathetic trunk stimulation. Epinephrine concentration was not significantly different in these three stages.
Diederichs, W. +3 more
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Effect of methylphenidate treatment during adolescence on norepinephrine transporter function in orbitofrontal cortex in a rat model of attention deficit hyperactivity disorder [PDF]
, 2015 Attention deficit hyperactivity disorder (ADHD) is associated with hypofunctional medial prefrontal cortex (mPFC) and orbitofrontal cortex (OFC). Methylphenidate (MPH) remediates ADHD, in part, by inhibiting the norepinephrine transporter (NET). MPH also
Dwoskin, Linda P. +2 more
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Effect of early vasopressin vs norepinephrine on kidney failure in patients with septic shock. The VANISH Randomized Clinical Trial [PDF]
, 2016 IMPORTANCE: Norepinephrine is currently recommended as the first-line vasopressor in septic shock; however, early vasopressin use has been proposed as an alternative.
Andrews, P +102 more
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Comparison of first-line and second-line terlipressin versus sole norepinephrine in fulminant ovine septic shock [PDF]
, 2018 The Surviving Sepsis Guidelines suggest the use of vasopressin in case of catecholamine-refractory septic shock. Terlipressin (TP) as a V-1-selective AVP analogue is a potential alternative, though data regarding the first-line administration in septic ...
Arnemann, Philip H +7 more
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Terlipressin or norepinephrine in septic shock: do we have the answer? [PDF]
, 2019 Comment on Terlipressin versus norepinephrine as infusion in patients with septic shock: a multicentre, randomised, double-blinded trial.
Russell, James A., Williams, Mark D.
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Inadvertent Extravasations of Norepinephrine
Clinical Case Reports, 2022 A 63-year-old male patient of diabetic ketoacidosis and septic shock was started on norepinephrine infusion following which he developed bulla and subcutaneous tissue ischemia in the event of inadvertent extravasations of norepinephrine. The patient improved after management with mechanical debridement of necrosed tissue and regular dressing of the ...
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Total norepinephrine spillover. [PDF]
Hypertension, 1988 Udgivelsesdato: 1988 ...
Christensen, N J +1 more
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Organic Cation Transporter 3: A Cellular Mechanism Underlying Rapid, Non-Genomic Glucocorticoid Regulation of Monoaminergic Neurotransmission, Physiology, and Behavior [PDF]
, 2018 Corticosteroid hormones act at intracellular glucocorticoid receptors (GR) and mineralocorticoid receptors (MR) to alter gene expression, leading to diverse physiological and behavioral responses.
Gasser, Paul J., Lowry, Christopher A.
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Stress, norepinephrine and depression [PDF]
Acta Neuropsychiatrica, 2002 Experimental and clinical evidence implicates stress as a major predisposing factor in depression and other severe psychiatric disorders. In this review, evidence is presented to show how the impact of stress on the central sympathetic system leads to changes in the endocrine, immune and neurotransmitter axes which underlie the main clinical symptoms ...
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The importance of norepinephrine in depression
Neuropsychiatric Disease and Treatment, 2011 Depression is one of the most common psychological diseases with significant potential morbidity and mortality. Although the underlying pathophysiology of depression has not been clearly defined, preclinical and clinical evidence suggest disturbances in serotonin (5-HT), norepinephrine (NE), and dopamine (DA) neurotransmission in the central nervous ...
Chantal Moret, Mike Briley
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