Results 11 to 20 of about 131,387 (308)

The role of nitric oxide in the dorsomedial periaqueductal gray (dmPAG) column in cardiovascular responses in urethane‐anesthetized male rats

open access: yesAnimal Models and Experimental Medicine, Volume 5, Issue 6, Page 557-564, December 2022., 2022
In the current study, after anesthetized rat with urethan the femoral artery was cannulated, then its head was mounted on a stereotaxic instrument and drugs (saline‐NAME, L‐Arg, and L_Arg+ L‐NAME) microinjected into the dmPAG and cardiovascular responses that recorded by a Power lab were evaluated.
Mohammad Najaftomaraei   +5 more
wiley   +1 more source

Association between acute kidney injury and norepinephrine use following cardiac surgery: a retrospective propensity score-weighted analysis

open access: yesAnnals of Intensive Care, 2022
Background Excess exposure to norepinephrine can compromise microcirculation and organ function. We aimed to assess the association between norepinephrine exposure and acute kidney injury (AKI) and intensive care unit (ICU) mortality after cardiac ...
Pierre Huette   +11 more
doaj   +1 more source

Inadvertent Extravasations of Norepinephrine

open access: yesClinical Case Reports, 2022
A 63-year-old male patient of diabetic ketoacidosis and septic shock was started on norepinephrine infusion following which he developed bulla and subcutaneous tissue ischemia in the event of inadvertent extravasations of norepinephrine. The patient improved after management with mechanical debridement of necrosed tissue and regular dressing of the ...
openaire   +2 more sources

Total norepinephrine spillover. [PDF]

open access: yesHypertension, 1988
Udgivelsesdato: 1988 ...
Christensen, N J   +1 more
openaire   +3 more sources

Structure‐guided identification of a selective sulfonamide‐based inhibitor targeting the human carbonic anhydrase VA isoform

open access: yesArchiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
Combining ligand‐based and structure‐based methodologies, the applied virtual screening approach identified a collection of sulfonamides targeting the human carbonic anhydrase (hCA) VA isoform. 2‐(3,4‐Dihydro‐2H‐quinolin‐1‐yl)‐N‐(4‐sulfamoylphenyl)acetamide was identified as a potent and selective lead compound as a candidate for further exploitation ...
Laura De Luca   +4 more
wiley   +1 more source

Norepinephrine as a Potential Aggravator of Symptomatic Cerebral Vasospasm: Two Cases and Argument for Milrinone Therapy

open access: yesCase Reports in Critical Care, 2014
Background. During hypertensive therapy for post-subarachnoid hemorrhage (SAH) symptomatic vasospasm, norepinephrine is commonly used to reach target blood pressures. Concerns over aggravation of vasospasm with norepinephrine exist. Objective.
F. A. Zeiler   +4 more
doaj   +1 more source

Norepinephrine-evoked pain in fibromyalgia. A randomized pilot study [ISRCTN70707830]

open access: yesBMC Musculoskeletal Disorders, 2002
Background Fibromyalgia syndrome displays sympathetically maintained pain features such as frequent post-traumatic onset and stimuli-independent pain accompanied by allodynia and paresthesias.
Casanova Jose-Miguel   +5 more
doaj   +1 more source

Stress, norepinephrine and depression [PDF]

open access: yesActa Neuropsychiatrica, 2002
Experimental and clinical evidence implicates stress as a major predisposing factor in depression and other severe psychiatric disorders. In this review, evidence is presented to show how the impact of stress on the central sympathetic system leads to changes in the endocrine, immune and neurotransmitter axes which underlie the main clinical symptoms ...
openaire   +3 more sources

How Is the Norepinephrine System Involved in the Antiepileptic Effects of Vagus Nerve Stimulation?

open access: yesFrontiers in Neuroscience, 2021
Vagus Nerve Stimulation (VNS) is an adjunctive treatment for patients suffering from inoperable drug-resistant epilepsy. Although a complete understanding of the mediators involved in the antiepileptic effects of VNS and their complex interactions is ...
Alexandre Berger   +11 more
doaj   +1 more source

The importance of norepinephrine in depression

open access: yesNeuropsychiatric Disease and Treatment, 2011
Depression is one of the most common psychological diseases with significant potential morbidity and mortality. Although the underlying pathophysiology of depression has not been clearly defined, preclinical and clinical evidence suggest disturbances in serotonin (5-HT), norepinephrine (NE), and dopamine (DA) neurotransmission in the central nervous ...
Chantal Moret, Mike Briley
openaire   +5 more sources

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