Results 41 to 50 of about 251,076 (337)

Human norepinephrine metabolism [PDF]

Journal of Clinical Investigation, 1971
It has become increasingly apparent that evaluation of human norepinephrine metabolism simply by assay of catecholamines in urine is inadequate for differentiation of many physiological or pathological states. In an attempt to examine norepinepherine metabolism in the human subject, tritium-labeled d,l-norepinephrine was administered to 11 normal ...
Laura M. Bertani, Wilkek, Stanley E. Gitlow, Milton Mendlowitz, Sherwin Wilk   +4 more
openaire   +2 more sources

Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE₂ in primary rat microglia

Journal of Neuroinflammation, 2010
Background Recent studies suggest an important role for neurotransmitters as modulators of inflammation. Neuroinflammatory mediators such as cytokines and molecules of the arachidonic acid pathway are generated and released by microglia.
Candelario-Jalil Eduardo, de Oliveira Antonio CP, Haake Elisabeth, Fiebich Bernd L, Schlachetzki Johannes CM, Heneka Michael T, Hüll Michael   +6 more
doaj   +1 more source

Norepinephrine affects the interaction of adherent-invasive Escherichia coli with intestinal epithelial cells

Virulence, 2021
Norepinephrine (NE), the stress hormone, stimulates many bacterial species’ growth and virulence, including Escherichia coli. However, the hormone’s impact on the adherent-invasive E. coli (AIEC) implicated in Crohn’s disease is poorly understood. In the
Sobieszczańska Beata, Turniak Michał, Olbromski Mateusz, Walczuk Urszula, Marcin Choroszy, Tukiendorf Andrzej, Dzięgiel Piotr   +6 more
doaj   +1 more source

Plasma norepinephrine and mortality [PDF]

Clinical Cardiology, 1995
Plasma norepinephrine levels, which reflect sympathetic nervous system activity, are almost universally elevated in patients with left ventricular dysfunction. This elevation occurs in patients with overt, symptomatic heart failure (HF) and in patients with asymptomatic left ventricular dysfunction.
openaire   +2 more sources

The Action of Norepinephrine, Epinephrine and Isopropyl Norepinephrine on the Rhythmic Function of the Heart [PDF]

Circulation, 1952
The actions of norepinephrine and isopropyl norepinephrine on the rhythmic property of the heart were studied and compared with that of epinephrine. Norepinephrine does not abolish cardiac standstill by carotid sinus stimulation, has no effect on the ventricular rate of heart block and induces a sinus bradycardia.
Morris H. Nathanson, Harold Miller
openaire   +3 more sources

Preclinical discovery of duloxetine for the treatment of depression [PDF]

, 2012
Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most ...
Berrocoso Domínguez, Esther María, Elorza, Julián, Micó Segura, Juan Antonio, Perez-Caballero, Laura, Torres-Sanchez, Sonia   +4 more
core   +2 more sources

Convergence of Pro-Stress and Pro-Inflammatory Signaling in the Central Noradrenergic System: Implications for Mood and Anxiety Disorders

Neuroglia, 2023
Mood and anxiety disorders are heterogeneous psychiatric diagnoses affecting millions. While the disease etiology is complex, various risk factors have been identified, such as stress.
Arthur Anthony A. Reyes, Daniel J. Chandler   +1 more
doaj   +1 more source

Comparison between norepinephrine plus epinephrine and norepinephrine plus vasopressin after return of spontaneous circulation in patients with out-of-hospital cardiac arrest

Scientific Reports
There is insufficient evidence regarding the use of second-line vasopressors following norepinephrine administration in the post-resuscitation management of patients with out-of-hospital cardiac arrest (OHCA).
Sejoong Ahn, Bo-Yeong Jin, Sukyo Lee, Jong-Hak Park, Hanjin Cho, Sungwoo Moon, Korean Cardiac Arrest Research Consortium (KoCARC) Investigators   +6 more
doaj   +1 more source

Norepinephrine Involvement in the Intermittent Swim Stress-Induced Deficit in Spatial Learning and Memory [PDF]

, 2013
Learning and memory impairments are often caused by stress disorders including depression. The present study investigated the involvement of norepinephrine in the swim stress-induced deficits of spatial learning and memory.
Elgert, Emily
core   +2 more sources

Norepinephrine and dopamine increase motility, biofilm formation and virulence of Vibrio harveyi [PDF]

, 2014
Vibrio harveyi is one of the major pathogens of aquatic organisms, affecting both vertebrates and invertebrates, and causes important losses in the aquaculture industry.
Bossier, Peter, Defoirdt, Tom, Nguyen Duc, Quynh Anh, Yang, Qian   +3 more
core   +2 more sources