Results 61 to 70 of about 4,862 (192)

The effectiveness of drug therapy, relaxation and compound therapy on anxiety reduction, level of epinephrine and norepinephrine among patients with generalized anxiety disorder

open access: yesفصلنامه دانشگاه علوم پزشکی جهرم, 2012
Introduction: Anxiety disorders are the most common psychiatric diseases in need of allocating high levels of health care services. This study aims to compare the effectiveness of drug therapy and relaxation on anxiety reduction and epinephrine and ...
E Hosseini, Z Tadayon
doaj  

Dual‐Channel Interdigitated Aptamer‐Based Sensors for Rapid Small‐Molecule Detection in Biofluids

open access: yesAngewandte Chemie International Edition, EarlyView.
An electrochemical aptamer sensing chip employs dual interdigitated electrodes and selective self‐assembled monolayer removal to convert small‐molecule recognition into robust “signal‐off/on” responses. This dual‐channel signal conversion minimizes background noise and accelerates probe diffusion, enabling rapid (as fast as 5–30 min), low‐volume ...
Senyao Wang   +12 more
wiley   +1 more source

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

open access: yesAutism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin   +3 more
wiley   +1 more source

Linking Brain Morphometry to Psychometric Measures and Energy‐Metabolic Biomarkers in Adults With Autism Spectrum Disorder

open access: yesAutism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is associated with differences in neurodevelopment and altered metabolism, yet the interplay between brain morphometry, mitochondrial and energy metabolism biomarkers, and autistic traits in adults remains poorly understood. This study investigates the link between brain structure, psychometric measures, and both
Eleonora Esposto   +10 more
wiley   +1 more source

Innovative therapeutic strategies using ADHD medications tailored to the behavioral characteristics of patients with chronic pain

open access: yesFrontiers in Pharmacology
Chronic pain affects a significant portion of adults and is linked to psychosocial issues, cognitive dysfunction, and psychiatric disorders, complicating treatment.
Satoshi Kasahara   +6 more
doaj   +1 more source

Thermoregulation and Norepinephrine [PDF]

open access: yesScience, 1969
R D, Meyers, M A, Simmonds, L L, Iversen
openaire   +2 more sources

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

Norepinephrine Induces PTSD-Like Memory Impairments via Regulation of the β-Adrenoceptor-cAMP/PKA and CaMK II/PKC Systems in the Basolateral Amygdala

open access: yesFrontiers in Behavioral Neuroscience, 2019
Glucocorticoids (GCs) can modulate the memory enhancement process during stressful events, and this modulation requires arousal-induced norepinephrine (NE) activation in the basolateral amygdale (BLA).
Xiang-Hui Liu   +14 more
doaj   +1 more source

Risk of injury associated with the sedative potential of second‐generation antihistamines: A nationwide retrospective cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi   +3 more
wiley   +1 more source

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