Results 71 to 80 of about 36,448 (236)

Brain Norepinephrine: Neurobiology and Therapeutics

open access: yes, 2007
This book was first published in 2007. Norepinephrine is a chemical neurotransmitter. Drugs that directly manipulate central nervous system (CNS) norepinephrine are being developed targeting noradrenergic neurons to deliver therapeutic effects ...
Ordwat, Gregory A.   +2 more
core   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

open access: yesAdvanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao   +9 more
wiley   +1 more source

Effects of Norepinephrine-Ephedrine Combination on Maternal Hemodynamics in Cesarean Sections Performed Under Spinal Anesthesia

open access: yesTrends in Surgical Sciences
Objective: The frequency of maternal hypotension after spinal anesthesia in Caesarean section (CS) may be as high as 90%. The aim of this study was to investigate the effect of the use of the combination of ephedrine and norepinephrine on maternal ...
Nurçin Gülhaş   +3 more
doaj   +1 more source

Norepinephrine-facilitated eating: reduction in saccharin preference and conditioned flavor preferences with increase in quinine aversion

open access: yes, 1985
Paraventricular (PVN) hypothalamic norepinephrine (NE) injections which facilitated feeding were nonetheless found to reduce both the unconditioned preference for saccharin and starch-conditioned preferences for almond odor and lemon taste, as well as ...
J W Matthews (16222829)   +2 more
core  

Limited Agreement Between Perceptual and Physiological Heat Strain at Initial Stay Times for Continuous Work in the Heat Before Heat Alleviation Controls

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Introduction Accurate assessment of heat strain at initial stay time (IST; core temperature 38.0°C or Δ1.0°C above resting), when heat mitigation decisions are required, is critical for managing occupational heat exposure. We evaluated the relationship and agreement between physiological (Physiological Strain Index [PSI] and adaptive PSI [aPSI]
Gil Bourgois   +4 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

Norepinephrine can Act via α2-Adrenoceptors to Reduce the Hyper-excitability of Spinal Dorsal Horn Neurons Following Chronic Nerve Injury

open access: yesJournal of the Formosan Medical Association, 2010
Rats display behavioral signs of neuropathic pain lasting for months in the chronic constriction injury (CCI) model. During intrathecal anesthesia, the administered drugs mainly diffuse directly into the superficial neurons in the spinal dorsal horn ...
Lu-Yang Jiang   +4 more
doaj   +1 more source

Trace Elements Genetics: A Potential Role in Treatment‐Resistant Major Psychoses and Related Traits?

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Trace elements are pivotal to key biological processes, with possible effects on psychopathology. We investigated the hypothesis of shared genetic factors between trace elements levels, treatment resistance and related traits. We used genome‐wide summary statistics for trace elements blood concentration, treatment‐resistant depression (TRD ...
Chiara Fabbri   +6 more
wiley   +1 more source

Fractal phototherapy: impact on the structure and function of the retina of rabbits with modelled retinal pigment epithelium atrophy

open access: yesРоссийский офтальмологический журнал
It is believed that in degenerative diseases of the retina, photostimulation by fractal dynamics signals activates neuroplasticity, thereby increasing the efficiency of visual rehabilitation.
D. V. Fadeev   +9 more
doaj   +1 more source

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