Results 91 to 100 of about 176,090 (288)
Handling of tracer norepinephrine by the dog liver
, 1989 Norepinephrine handling by the dog liver was appraised by carrying out tracer-transient, multiple-indicator-dilution studies within steady-state conditions in a basal situation, during norepinephrine infusion and after the uptake inhibitor desipramine ...
A. J. Schwab +6 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley +1 more source
Frontiers in PharmacologyChronic pain affects a significant portion of adults and is linked to psychosocial issues, cognitive dysfunction, and psychiatric disorders, complicating treatment.
Satoshi Kasahara +6 more
doaj +1 more source
Effect of hemorrhagic shock on release of norepinephrine by tyramine
, 1964 This study was undertaken to determine if the sympathetic discharge which accompanies hemorrhagic shock modifies the response to tyramine. In eight dogs the dose of tyramine equipressor to 1.0 µg/kg min of norepinephrine was 85 ± 8 µg/kg min in the ...
Donald C. Harrison +2 more
core +1 more source
Translational development of crisugabalin for neuropathic pain
British Journal of Clinical Pharmacology, EarlyView.Abstract Crisugabalin (HSK16149) is a next‐generation α2δ ligand developed to preserve the mechanistic rationale of gabapentinoids while refining target engagement and exposure‐related tolerability constraints. We performed a translational review of molecular/structural studies, in vivo pharmacology and behavioural safety assessments, phase I clinical ...
Rafael Batista João +5 more
wiley +1 more source
Fat expansion through norepinephrine catabolism
, 2017 Certain macrophage populations limit norepinephrine-induced lipolysis in adipose tissues in response to aging or obesity.
Wei Wong
core +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
BMEMat, EarlyView.This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2019 Glucocorticoids (GCs) can modulate the memory enhancement process during stressful events, and this modulation requires arousal-induced norepinephrine (NE) activation in the basolateral amygdale (BLA).
Xiang-Hui Liu +14 more
doaj +1 more source
Biological Reviews, EarlyView.ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino +7 more
wiley +1 more source
Acne and Stress: Impact of Catecholamines on Cutibacterium acnes
Frontiers in Medicine, 2019 Cutibacterium acnes (former Propionibacterium acnes), is a bacterium characterized by high genomic variability, consisting of four subtypes and six major ribotypes.
Valérie Borrel +8 more
doaj +1 more source