Results 101 to 110 of about 176,090 (288)

Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration [PDF]

open access: yes, 2008
: INTRODUCTION: Low blood pressure, inadequate tissue oxygen delivery and mitochondrial dysfunction have all been implicated in the development of sepsis-induced organ failure.
Gorrasi, Jose   +23 more
core   +2 more sources

Motor Physiology Transcranial Magnetic Stimulation–Based Biomarkers and Associated Neurocognitive Profiles in Attention‐Deficit/Hyperactivity Disorder

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Purpose Attention‐deficit/hyperactivity disorder (ADHD) is a highly prevalent and heterogeneous neurodevelopmental condition for which current diagnostic approaches rely on symptom‐based classifications that do not capture underlying neurobiology.
Alyssa C. DeRonda   +7 more
wiley   +1 more source

Direct action of norepinephrine on aortic baroreceptors of rat adventitia

open access: yes, 1984
The adventitia of the rat aortic arch, with the depressor nerve intact, was separated from the underlying media to obtain a preparation in which the direct effects of norepinephrine on baroreceptor discharge could be examined free of smooth muscle ...
C. J. Orlea, J. M. Krauhs, D. L. Kunze
core   +1 more source

Norepinephrine-Induced DNA Damage in Ovarian Cancer Cells

open access: yes, 2020
Multiple studies have shown that psychological distress in epithelial ovarian cancer (EOC) patients is associated with worse quality of life and poor treatment adherence. This may influence chemotherapy response and prognosis.
Arelis Acevedo-Santiago   +5 more
core   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples   +10 more
wiley   +1 more source

Pulmonary function during norepinephrine-induced calorigenesis in cold-acclimatized rats

open access: yes, 1963
The effects of cold acclimatization on pulmonary function during norepinephrine-induced calorigenesis were studied. Norepinephrine resulted in a marked increase (85%) in the pulmonary minute volume in both the warm- and cold-acclimatized rats.
John P. Hannon, Eugene Evonuk
core   +1 more source

Tramadol Co‐Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Tramadol is frequently co‐prescribed with oxycodone or hydrocodone after surgery under the assumption that its dual mechanism of action provides an opioid‐sparing benefit. However, evidence supporting this practice is limited and inconsistent. We conducted a secondary analysis of the multicenter IGNITE ADOPT‐PGx pragmatic trial of patients undergoing ...
Noor A. Nahid   +302 more
wiley   +1 more source

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung   +12 more
wiley   +1 more source

β-adrenergic receptor-induced E-S potentiation in the dorsal and ventral hippocampus

open access: yesFrontiers in Synaptic Neuroscience
β-adrenergic receptors (β-ARs) play a critical role in modulating learning, memory, emotionality, and long-term synaptic plasticity. Recent studies indicate that β-ARs are necessary for long-term potentiation (LTP) induction in the ventral hippocampus ...
George Trompoukis   +2 more
doaj   +1 more source

Effects of chlorothiazide on forearm vascular responses to norepinephrine

open access: yes, 1961
The effects of graded doses of norepinephrine on pulse rate, mean blood pressure, forearm blood flow and vascular resistance were studied in normal human subjects before, during, and after chronic administration of chlorothiazide.
Khalil A. Feisal   +3 more
core   +1 more source

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