Results 131 to 140 of about 244,568 (170)

Norethindrone acetate and estradiol-induced endometrial hyperplasia

Obstetrics & Gynecology, 2000
To identify the lowest effective continuous dose of norethindrone acetate that significantly reduces 12-month incidence of endometrial hyperplasia associated with unopposed 17beta-estradiol (E2), 1 mg.In a double-masked, randomized, multicenter study, 1176 healthy postmenopausal women 45 years of age or older without evidence of endometrial ...
R J, Kurman, J C, Félix, D F, Archer, N, Nanavati, J, Arce, D L, Moyer   +5 more
openaire   +2 more sources

Clinical evaluation of norethindrone acetate in fertility control

American Journal of Obstetrics and Gynecology, 1965
A clinical evaluation of 300 Mexican women accumulating 5902 treatment cycles representing 454 woman-years with 4 mg norethindrone acetate and .05 mg ethinyl estradiol (Anovlar) is presented. Each woman was instructed to take 1 tablet daily for 20 consecutive days beginning on Cycle Day 5. Anovlar was virtually 100% effective.
E, RICE WRAY, O, GONZALEZ, S, FERRER, A, ARANDA ROSELL, M, MAQUEO, H, MUNGUIA   +5 more
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Hydrolysis of Norethindrone Acetate by Fetal and Placental Tissue

New England Journal of Medicine, 1963
IT has been demonstrated that certain progestational agents given during pregnancy may result in masculinization of the female fetus.1 , 2 The agent most frequently implicated was norethindrone (Norlutin). This drug has now been largely superseded in clinical use by its more potent ester, norethindrone acetate (Norlutate).
G, BETZ, J C, WARREN
openaire   +2 more sources

Bioavailability of norethindrone and menstrual pattern after insertion of norethindrone acetate implants in rhesus monkeys

Contraception, 1991
Subdermal silastic implants releasing norethindrone acetate were inserted in five rhesus monkeys for a period of seven months. The serum norethindrone (NET) levels were estimated from blood samples collected fortnightly. There was an initial high level of NET followed by fluctuating levels of NET in 4 out of five monkeys.
P, Jha, K, Murugesan, A, Farooq
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Radioimmunoassay of norethindrone: Serum levels of norethindrone in lactating women after insertion of a single silastic implant releasing norethindrone acetate

Contraception, 1978
A specific radioimmunoassay was developed for the estimation of norethindrone levels in the serum of lactating women. A conjugate of norethindrone-3-BSA was synthesized and antiserum raised against it in rabbits. The antiserum showed high affinity (1.5 x 10(9)M/L) and titer and was specific. The sensitivity of the assay was 125 pg/ml serum.
V, Laumas, B K, Malik, K, Jamal, U, Seth, N, Agarwal, V, Hingorani, K R, Laumas   +6 more
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A Contraceptive Vaginal Ring Releasing Norethindrone Acetate and Ethinyl Estradiol

Obstetrical & Gynecological Survey, 1994
A core design contraceptive vaginal ring (CVR) releasing 650 mcg of norethindrone acetate (NA) and 10, 20, 30 or 65 mcg of ethinyl estradiol (EE) daily was developed and tested in 99 women. The CVR inhibited ovulation well with 30 or 65 mcg EE. Vaginal bleeding was better controlled than in 23 control women using NA/EE oral contraceptives. Side effects
S A, Ballagh, D R, Mishell, M, Lacarra, D, Shoupe, T M, Jackanicz, P, Eggena   +5 more
openaire   +2 more sources

Programming of ovarian stimulation with norethindrone acetate in IVF/GIFT cycles

Human Reproduction, 1989
Twenty patients were given norethindrone acetate (NET) to program the initiation of controlled ovarian hyperstimulation and to coordinate follicular aspiration with surgery to obtain spermatozoa from the husband. Patients received NET, 10 mg/day orally, starting between days 2 and 4 of the cycle.
GERLI, Sandro, Remohi J, Patrizio P, Borrero C, Balmaceda JP, Silber S, Asch RH   +6 more
openaire   +4 more sources

Effect of Norethindrone Acetate Upon Gonadotrophin-Induced Ovarian Function

The Journal of Clinical Endocrinology & Metabolism, 1965
Ovarian function was successfully induced in 2 successive cycles in 2 amenorrheic women using urinary gonadotrophins. When 5 mg of norethindrone acetate was administered along with the gonadotrophin ovarian function persisted. It was concluded that this is further evidence that this dosage of norethindrone acetate inhibits ovulation by suppression of ...
M L, TAYMOR, T, RIZKALLAH
openaire   +2 more sources

Pharmacology and Toxicology of Ethinyl Estradiol and Norethindrone Acetate in Experimental Animals

Regulatory Toxicology and Pharmacology, 2001
For over 30 years various combinations of synthetic estrogens and progestins have been used in oral contraceptive formulations. Ethinyl estradiol (EE) and norethindrone acetate (NA) are common synthetic hormones used in oral contraceptives such as Loestrin, Brevicon, Ortho-Novum, Norlestrin, and Norinyl.
W E, Maier, J R, Herman
openaire   +2 more sources

Metabolic and endocrine studies in women using norethindrone acetate implant

Contraception, 1979
Subcutaneously administered implant-D containing 40 mg of Norethindrone acetate in a single silastic implant was offered to 79 subjects who desired spacing of their family. The effect of constant release of steroid from this device on metabolic and endocrine functions was studied. Each subject in the pretreatment state served as her own control.
S M, Shahani, P P, Kulkarni, P A, Bhate, K L, Patel   +3 more
openaire   +2 more sources