Results 41 to 50 of about 244,568 (170)

Bleeding patterns in postmenopausal women using continuous combination hormone replacement therapy with conjugated estrogen and medroxyprogesterone acetate or with 17β-estradiol and norethindrone acetate

, 2001
OBJECTIVE: We studied bleeding patterns in postmenopausal women who were using 2 types of continuous combination regimens. STUDY DESIGN: A prospective, double-blind, randomized study of 208 postmenopausal women treated with conjugated estrogen, 0.625 mg,
Torbjörn Bäckström, Jonsson, Björn,, Ödmark, Inga-Stina,, Björn Jonsson, Bäckström, Torbjörn,, Inga-Stina Ödmark   +5 more
core   +1 more source

Membranous dysmenorrhea and decidual casts: A scoping review

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Membranous dysmenorrhea, characterized by the expulsion of intact endometrial tissue rather than gradual dissolution during menstruation, occasionally presents as a decidual cast—a complete triangular mold of the uterine cavity. This poorly understood condition is likely underdiagnosed.
Lovisa Brehmer, Hedvig Engberg
wiley   +1 more source

Formation of Ethinyl Estradiol in Women during Treatment with Norethindrone Acetate [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2007
The significance of the conversion of norethindrone acetate (NET-A), a commonly prescribed, synthetic, oral progestogen, to ethinyl estradiol (EE(2)) is controversial.We sought to determine accurately the extent to which NET-A may be converted to EE(2), and if so, whether circulating levels of EE(2) would be of clinical significance.
Micheline C, Chu, Xiaohua, Zhang, Elisabet, Gentzschein, Frank Z, Stanczyk, Rogerio A, Lobo   +4 more
openaire   +2 more sources

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas, Olivia Carere, Lauren Clarfield, Michelle Jacobson   +3 more
wiley   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Progestin Pollution in Surface Waters of a Major Southwestern European Estuary: The Douro River Estuary (Iberian Peninsula)

Toxics
The concentrations and spreading of eight synthetic and two natural progestins (PGs) were investigated in surface waters from ten sites at the Douro River Estuary.
Frederico Silva, Rodrigo F. Alves, Eduardo Rocha, Maria João Rocha   +3 more
doaj   +1 more source

Endometriosis: Epidemiology, Risk Factors, Molecular Mechanisms, Diagnosis, and Management

MedComm, Volume 7, Issue 7, July 2026.
Global epidemiology, integrated determinants, and disease burden of endometriosis. This circular schematic comprehensively illustrates the global prevalence and demographic variation of endometriosis, its multifactorial integrated determinants, the multifaceted disease burden and economic impact, and recent epidemiological trends, providing a holistic ...
Kun Wang, Dongyun He, Yang Wang, Xiaojun Liu, Li Liu   +4 more
wiley   +1 more source

A concept for a new approach to combined oral contraception from adolescence to perimenopause: Continuous use of the oral GnRH antagonist Relugolix and the fetal estrogen Estetrol

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 4, Page 568-574, April 2026.
It is expected that the relugolix estetrol combination RE4W will enable women to control their fertility and prevent menstrual cycle related problems, while offering a smooth transition through perimenopause into the postmenopause and decrease the risk of breast cancer.
Herjan J. T. Coelingh Bennink, Karolina Afors, Luis Bahamondes, Alessandra Graziottin, Deborah Bateson, Teresa Bombas, Yutaki Osuga, Santiago Palacios, Carolyn L. Westhoff, Kristina Gemzell‐Danielsson   +9 more
wiley   +1 more source

Synthetic estrogen and progestin effects on the myogenic program following damage in C2C12 murine myoblasts

Physiological Reports, Volume 14, Issue 8, April 2026.
The effect of oral contraceptives (OCs) on muscle repair is unknown. Using electrical pulse stimulation to simulate damage in C2C12 myoblasts treated with four OC generations (MPA, LNG, DSG, DRP combined with ethinyl estradiol), we assessed proliferation, differentiation, migration, creatine kinase, myogenic proteins, and hormone receptor protein ...
Mai Wageh, Michael Kamal, Gianni Parise
wiley   +1 more source

Effect of norethisterone dose and duration in the management of abnormal uterine bleeding: a narrative review and case report

Drugs in Context
Abnormal uterine bleeding (AUB) is an acute/chronic variation in the normal menstrual cycle that affects adolescents, women of reproductive age and perimenopausal women.
Arun Madhab Boruah, Dibyendu Banerjee, Farendra Bhardwaj, Subash Mallya, Rajat Singal, Sugandha Sharma, Ashutosh Gautam   +6 more
doaj   +1 more source