Results 1 to 10 of about 3,411 (181)

A review of recommendations, efficacy, and patient safety for over-the-counter norgestrel for daily contraception [PDF]

open access: yesExploratory Research in Clinical and Social Pharmacy
Purpose: This narrative review examines the implications of norgestrel, a progestin-only oral contraceptive, becoming newly available over-the-counter (OTC) in the United States.
Gia Tran   +5 more
doaj   +2 more sources

Luteal blood flow in patients undergoing GnRH agonist long protocol [PDF]

open access: yesJournal of Ovarian Research, 2011
Background Blood flow in the corpus luteum (CL) is closely related to luteal function. It is unclear how luteal blood flow is regulated. Standardized ovarian-stimulation protocol with a gonadotropin-releasing hormone agonist (GnRHa long protocol) causes ...
Takasaki Akihisa   +10 more
doaj   +3 more sources

Progestogen use and the risk of intracranial meningioma: a systematic review and meta-analysisResearch in context [PDF]

open access: yesEClinicalMedicine
Summary: Background: Meningiomas are the most common primary brain tumours in adults. Concerns have emerged about a possible link between progestogen use and intracranial meningioma; we assessed this association.
Benoit Hudelist   +12 more
doaj   +2 more sources

Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling. [PDF]

open access: yesPLoS ONE, 2016
Retinitis pigmentosa (RP) is a degenerative disease leading to photoreceptor cell loss. Mouse models of RP, such as the rd10 mouse (B6.CXBl-Pde6brd10/J), have enhanced our understanding of the disease, allowing for development of potential therapeutics ...
Sarah L Roche   +7 more
doaj   +1 more source

Assessing the Pregnancy Protective Impact of Scheduled Nonadherence to a Novel Progestin-Only Pill: Protocol for a Prospective, Multicenter, Randomized, Crossover Study

open access: yesJMIR Research Protocols, 2021
BackgroundProgestin-only contraceptive pills (POP) are commonly reserved for women with medical comorbidities but in actuality, POPs can be safely used by anyone wanting to prevent pregnancy.
Edelman, Alison   +5 more
doaj   +1 more source

Miniaturized solid-phase microextraction coupled with gas chromatography-mass spectrometry for determination of endocrine disruptors in drinking water

open access: yesFood Chemistry: X, 2022
A simple and rapid method based on miniaturized solid-phase microextraction (mini-SPME) followed by gas chromatography–mass spectrometry was developed to identify eight endocrine disruptors (atrazine, diethylstilbestrol, hexestrol, estrone, estradiol ...
Mereke Alimzhanova   +4 more
doaj   +1 more source

Assessment of porphyrogenicity of drugs and chemicals in selected hepatic cell culture models through a fluorescence‐based screening assay

open access: yesPharmacology Research & Perspectives, 2022
Compounds that induce 5‐aminolevulinic acid [ALA] synthase‐1 and/or cytochromes P‐450 may induce acute porphyric attacks in patients with the acute hepatic porphyrias [AHPs].
Christopher D. Ma   +4 more
doaj   +1 more source

Progesterone analogue protects stressed photoreceptors via bFGF-mediated calcium influx. [PDF]

open access: yes, 2016
Retinitis pigmentosa (RP) is a degenerative retinal disease leading to photoreceptor cell loss. In 2011, our group identified the synthetic progesterone ‘Norgestrel’ as a potential treatment for RP.
Byrne, Ashleigh M.   +5 more
core   +1 more source

The synthetic progestin norgestrel modulates Nrf2 signaling and acts as an antioxidant in a model of retinal degeneration

open access: yesRedox Biology, 2016
Retinitis pigmentosa (RP) is one of the most common retinal degenerative conditions affecting people worldwide, and is currently incurable. It is characterized by the progressive loss of photoreceptors, in which the death of rod cells leads to the ...
Ashleigh M. Byrne   +5 more
doaj   +1 more source

Pro-survival redox signalling in progesterone-mediated retinal neuroprotection [PDF]

open access: yes, 2017
Retinitis pigmentosa (RP) is a group of hereditary retinal diseases, characterised by photoreceptor cell loss. Despite a substantial understanding of the mechanisms leading to cell death, an effective therapeutic strategy is sought.
Byrne, Ashleigh M.   +5 more
core   +1 more source

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