Results 41 to 50 of about 1,822 (206)

The Combined Effect of Obesity and Contraceptive Use on Pulmonary Embolism in Adolescent Females Residing in the United States

open access: yesPediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley   +1 more source

A concept for a new approach to combined oral contraception from adolescence to perimenopause: Continuous use of the oral GnRH antagonist Relugolix and the fetal estrogen Estetrol

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 4, Page 568-574, April 2026.
It is expected that the relugolix estetrol combination RE4W will enable women to control their fertility and prevent menstrual cycle related problems, while offering a smooth transition through perimenopause into the postmenopause and decrease the risk of breast cancer.
Herjan J. T. Coelingh Bennink   +9 more
wiley   +1 more source

Combined Oral Contraceptive Drug–Drug Interaction Study With Ganfeborole, a New Anti‐Tuberculosis Agent

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 3, March 2026.
Abstract New drugs are urgently needed to treat drug‐resistant tuberculosis in combination regimens. Ganfeborole demonstrated bactericidal activity and good tolerability in clinical trials. In preclinical studies, ganfeborole showed embryofetal developmental effects, currently mandating highly effective non‐user dependent contraception in women of ...
Laura Iavarone   +13 more
wiley   +1 more source

Norgestrel significantly abrogates rd10 microglial-induced 661W cell death.

open access: yes, 2016
(A) Conditioned media was collected from primary microglial cells cultured with (CM + NORG), or without (CM) 20 μM Norgestrel over 24 h. 661W cells were cultured over a further 24h in the absence (Control) or presence of conditioned media (CM, CM + NORG)
Nicolás Cuenca (142887)   +7 more
core   +1 more source

Simultaneous Determination of Hormonal Residues in Treated Waters Using Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry

open access: yesJournal of Analytical Methods in Chemistry, 2013
In the last years, hormone consumption has increased exponentially. Because of that, hormone compounds are considered emerging pollutants since several studies have determinted their presence in water influents and effluents of wastewater treatment ...
Rayco Guedes-Alonso   +2 more
doaj   +1 more source

Barriers to access to over-the-counter oral contraceptives by neighborhood social vulnerability in Boston, Massachusetts

open access: yesSexual & Reproductive Healthcare
Oral contraceptives are widely used in the US, but prescription requirements are an access barrier, particularly for adolescents and young adults. Over-the-counter availability of norgestrel 0.075 mg (OPill) was anticipated to improve contraceptive ...
Samantha Garbers   +3 more
doaj   +1 more source

Harnessing Algal Biorefineries for Waste to Wealth Paradigm: A Pathway Toward Circular and Sustainable Bioeconomy

open access: yesCleanMat, Volume 2, Issue 4, Page 297-326, December 2025.
This review highlights the use of wastewater from various sources including industrial, municipal, and agricultural effluents for microalgal cultivation. It emphasizes on the integrated approach of wastewater treatment and microalgal biomass production for high value‐added bioproducts such as biofuels, animal feed, biofertilizers, bioplastics while ...
Prachi Bhatnagar   +3 more
wiley   +1 more source

Norgestrel reduces pro-inflammatory and promotes anti-inflammatory phenotypes in rd10 microglia.

open access: yes, 2016
(A) RT-qPCR analysis detected similar levels of mRNAs encoding progesterone receptor membrane complexes 1 and 2 (PGRMC1, PGRMC2) and all three membrane progesterone receptor isoforms, α, β and γ (mPRα, mPRβ, mPRγ) in rd10 retinal microglial cells ...
Nicolás Cuenca (142887)   +7 more
core   +1 more source

Identifying Gene Predictors of Chemicals Linked With Breast Cancer: A Machine Learning Analysis of MCF7 Cellular Transcriptomic Screening Data

open access: yesEnvironmental and Molecular Mutagenesis, Volume 66, Issue 8, Page 425-441, October 2025.
ABSTRACT Breast cancer is the most prevalent cancer in women and has been linked to exposure to environmental chemicals. However, many chemicals have not been evaluated for relationships with this outcome. In this study, we analyzed RNA sequencing data from human breast cancer‐derived MCF7 cells exposed to hundreds of individual chemicals.
Lauren E. Koval   +2 more
wiley   +1 more source

Metabolism of orally administered D-Norgestrel in women

open access: yes, 1972
Tritiated D-norgestrel was administered orally to five women. Urine and plasma were collected for 4 days.In plasma the maximum tritium concentration is reached after 4 or 6 hours.
Schwers, Jean   +2 more
core   +1 more source

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