Results 61 to 70 of about 1,822 (206)

Disruption of reproductive and thyroid endocrine systems in zebrafish following early life and whole life cycle exposure to low-dose norgestrel

Ecotoxicology and Environmental Safety
Norgestrel (NGT), a synthetic progestin, is frequently detected in aquatic environments and known to disrupt fish endocrine systems. In this study, zebrafish embryos were exposed to low NGT concentrations (9 and 66 ng/L) for 90 days post-fertilization ...
Shuyan Mai, Weicai Hu, Yan-Qiu Liang, Zhongdian Dong, Chang-Gui Pan, Zhiyun Liu, Runting Ouyang, Yangjie Zeng, Zhong Lin, Liping Hou   +9 more
doaj   +1 more source

Male contraceptive acceptability versus male acceptance of contraceptive responsibility

Andrology, Volume 12, Issue 7, Page 1585-1589, October 2024.
Abstract Despite the projected impact of new male contraceptives, resources and investments directed at their development remain limited in part due to concerns that men would not actually use them. Now, more than 30 studies have been conducted over the last 30 years—regionally and internationally, within clinical trials, and across populations ...
Brian T. Nguyen
wiley   +1 more source

Thromboembolic adverse event study of combined estrogen-progestin preparations using Japanese Adverse Drug Event Report database.

PLoS ONE, 2017
Combined estrogen-progestin preparations (CEPs) are associated with thromboembolic (TE) side effects. The aim of this study was to evaluate the incidence of TE using the Japanese Adverse Drug Event Report (JADER) database.
Shiori Hasegawa, Toshinobu Matsui, Yuuki Hane, Junko Abe, Haruna Hatahira, Yumi Motooka, Sayaka Sasaoka, Akiho Fukuda, Misa Naganuma, Kouseki Hirade, Yukiko Takahashi, Yasutomi Kinosada, Mitsuhiro Nakamura   +12 more
doaj   +1 more source

Pregnancy outcomes after first‐trimester exposure to fluoroquinolones: Findings based on an integrated database from two Japanese institutions

Congenital Anomalies, Volume 64, Issue 5, Page 199-206, September 2024.
Abstract Given the paucity of safety data on fluoroquinolone antibiotics in pregnancy, a prospective observational cohort study was conducted in pregnant women who sought help and advice on drug use at two teratology information institutes in Japan. The primary endpoint of the study was the incidence of major congenital anomalies.
Mikako Goto, Tatsuhiko Anzai, Ritsuko Yamane, Naho Yakuwa, Kunihiko Takahashi, Atsuko Murashima   +5 more
wiley   +1 more source

Norgestrel preserves rod and cone outer segment morphology in the rd10 retina.

, 2016
Confocal microscopic images of (A) rod (rhodopsin; red) and (B) cone outer segments (PNA; green) in the central retina from P15-P40 of control and Norgestrel-fed rd10 mice.
Nicolás Cuenca (142887), Violeta Gómez-Vicente (797146), Ana M. Ruiz-Lopez (3332571), Pedro Lax (143830), Thomas G. Cotter (151944), Alice C. Wyse-Jackson (3332568), Sarah L. Roche (452321), Ashleigh M. Byrne (3332565)   +7 more
core   +1 more source

Photoprotective activities of Capsosiphon fulvescens in UVB‐induced SKH‐1 mice and human keratinocytes

Journal of Food Science, Volume 89, Issue 8, Page 5150-5163, August 2024.
Abstract Capsosiphon fulvescens (CF) is a green alga widely consumed in East Asian countries, particularly in Korea. It has a rich composition of vitamins, minerals, dietary fibers, and bioactive compounds, which contribute to its multiple therapeutic properties.
Jiwon Seo, Chanhyeok Jeong, Won Jo Choi, Jung Han Yoon Park, Chang Hyung Lee, Ki Won Lee   +5 more
wiley   +1 more source

Pregnandiol urinario con d-norgestrel postcoital

, 1973
The effect of the administration of D-Norgestrel on urinary excretion postcoital pregnanediol studied and found to not act as said progestin anovulatory at least to a limited extent delivered dose cycle.Se estudia el efecto de la administración del D ...
Kesseru, Esteban, Westphal, Norbert
core  

FOXL2 and NR5A1 induce human fibroblasts into steroidogenic ovarian granulosa‐like cells

Cell Proliferation, Volume 57, Issue 5, May 2024.
Overexpression of FOXL2 and NR5A1 reprogrammed human fibroblast cells into late‐stage and early‐stage granulosa cells respectively. AMH‐EGFP+ hiGCs secret high levels of estradiol and progesterone, and CD55+ hiGCs secret high level of estradiol. CD55+ hiGC transplantation can alleviate DHEA‐induced PCOS and has potential for cell therapy of PCOS ...
Fan Wen, Yuxi Ding, Mingming Wang, Jing Du, Shen Zhang, Kehkooi Kee   +5 more
wiley   +1 more source

Comparación de las complicaciones del levonorgestrel y la combinación norgestrel atinilestradiol – hospital Banda de Shilcayo período 1996 – 1997 [PDF]

, 1997
This research traba._io is a study of scriptivo, is also comparative with prospective data and so it was long! tudinal in time, which is an applied research, which was developed in the hospital, rural of the Banda de Shilcayo during the period from 1996 ...
Arce Saavedra, Segundo Nixon
core  

Progesterone analogue protects stressed photoreceptors via bFGF-mediated calcium influx. [PDF]

, 2016
Retinitis pigmentosa (RP) is a degenerative retinal disease leading to photoreceptor cell loss. In 2011, our group identified the synthetic progesterone ‘Norgestrel’ as a potential treatment for RP.
Roche, Sarah L., Moloney, Jennifer N., Alice C. Wyse‐Jackson, Ana M. Ruiz‐Lopez, Jennifer N. Moloney, Wyse-Jackson, Alice C., Byrne, Ashleigh M., Sarah L. Roche, Ashleigh M. Byrne, Ruiz-Lopez, Ana M., Thomas G. Cotter, Cotter, Thomas G.   +11 more
core   +1 more source