Results 71 to 80 of about 1,822 (206)

Occurrence and ecological risks of endocrine-disrupting chemicals in three National Aquatic Germplasm Resources Reserves in the South China Sea

Environmental Chemistry and Ecotoxicology
National Aquatic Germplasm Resources Reserves (NAGRRs) are pivotal protected areas in delivering ecological and socio-economic advantages. This study focuses on three NAGRRs in the South China Sea, meticulously examining the pollution levels of 31 common
Chong Chen, Huadong Yi, Shaopeng Xu, Yutong Zhang, Qihui Zhao, Ruolan Jia, Chengcheng Bu, Xian Qin, Sheng Bi, Limin Ma, Guifeng Li, Kenneth Mei Yee Leung, Yuefei Ruan   +12 more
doaj   +1 more source

Determination of ethinylestradiol and norgestrel in water using solid-phase microextraction

, 2016
Endocrine disrupting compounds (EDCs) are exogenous substances that alter some function of the endocrine system and have adverse health effects on intact organisms, their off spring or (sub)populations. EDCs mimic or block the action of natural hormones,
Svetlana Batyrbekova, Yerlan Adilbekov, Yenglik Nurzhanova, Mereke Alimzhanova   +3 more
core   +1 more source

Genomic and transcriptomic characterization of a novel wastewater-derived Sporosarcina sp. with broad-spectrum bioremediation potential against endocrine disruptors and pharmaceuticals

Chemical Engineering Journal Advances
Emerging pollutants (EPs) such as pharmaceuticals, hormones, and pesticides are increasingly detected in aquatic environments due to their widespread use and incomplete removal by conventional wastewater treatment plants.
Sumayya Al Ali, Khadije Ahmad Amin, Aryam Alkaabi, Hima Vadakkeveettil Manoharan, Michael Olbrich, Ahmed F. Yousef, Habiba Al Safar, Syed Salman Ashraf, Gihan Daw Elbait   +8 more
doaj   +1 more source

GENOTOXIC AND CARCINOGENIC STUDIES OF NORGESTREL IN DROSOPHILA MELANOGASTER [PDF]

, 2018
Objective: The aim of this study was to investigate, for the first time, the possible in vivo genotoxic and carcinogenic activity associated with exposure to norgestrel (NGT) drug through employing the very recently established and adjusted genotoxic and
ABOU-EISHA, AHMED, El-din, Adel E
core   +1 more source

Design of Potential Anti-Leishmanial Pharmacophores via In Silico Drug Repurposing

Journal of Ardabil University of Medical Sciences, 2020
Background & objectives: Drug-repurposing is the study on application of existing drugs for treatment or control of other diseases. Major advantage of the technique relies on a nominated drug molecule that is applied for pharmacodynamics optimization due
Sana Ahdeno, Nima Razaghi-Asl, Behnam Mohammadi-ghalehbin   +2 more
doaj  

Pro-survival redox signalling in progesterone-mediated retinal neuroprotection [PDF]

, 2017
Retinitis pigmentosa (RP) is a group of hereditary retinal diseases, characterised by photoreceptor cell loss. Despite a substantial understanding of the mechanisms leading to cell death, an effective therapeutic strategy is sought.
Roche, Sarah L., Moloney, Jennifer N., Jennifer N. Moloney, Ruiz López, Ana M., Wyse-Jackson, Alice C., Byrne, Ashleigh M., Sarah L. Roche, Alice C. Wyse Jackson, Ashleigh M. Byrne, Thomas G. Cotter, Ana M. Ruiz Lopez, Cotter, Thomas G.   +11 more
core   +1 more source

Steroid induced neuroprotection of damaged photoreceptor cells [PDF]

, 2016
Retinitis Pigmentosa (RP) is the name given to a group of hereditary diseases causing progressive and degenerative blindness. RP affects over 1 in 4000 individuals, making it the most prevalent inherited retinal disease worldwide, yet currently there is ...
Wyse-Jackson, Alice C.
core   +1 more source

Evaluación clínica de dos preparados bifásicos y un trifásico a base de norgestrel/etinilestradiol

, 1981
458 women were evaluated during 3585 cycles in a randomized, open controlled study designed to compare two two-phase and three-phase preparations based Norgestrel / Etilnilestradiol. The three preparations are not effective contraceptives and pregnancies
Larrañaga, Alfredo
core  

Questions in self‐selection studies used in consumer research for nonprescription drug candidates: Limitations and recommendations

Clinical and Translational Science
Self‐selection studies assess participants' ability to use label information to decide if a proposed nonprescription drug is appropriate for their use. The optimal use of information from participants' responses in these trials has not been studied. Data
Eric P. Brass, Russell D. Bradford, Arthur Stone   +2 more
doaj   +1 more source

Effectiveness of Intrauterine Levonorgesterel-Releasing Device in the Treatment of Endometrial Hyperplasia in Obese Patients

Acta Medica Alanya
Aim: Endometrial hyperplasia (EH) is a precursor lesion of endometrial adenocarcinoma, the most common gynecological malignancy in women. Endometrial hyperplasias divided in two groups: non-atypical hyperplasia and atypical hyperplasia.
Işıl Çiçekdağı, Sezin Ateş
doaj