Results 131 to 140 of about 2,274,755 (343)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

A User's Guide to Network Analysis in R

open access: yesJournal of Statistical Software, 2016
Norm Matloff
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Technical Evaluation Report 46. CanCore: in Canada and Around the World

open access: yesInternational Review of Research in Open and Distributed Learning, 2005
The current report provides an update on Report #11 and Report #40 in this series, describing the increasing range of international uses of the CanCore metadata for the indexing of learning objects.
Norm Friesen
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

COVID-19 pandemic impact on microfinance industry

open access: yesFuture Business Journal
The COVID-19 pandemic is the world’s deadliest health pandemic since the 1918 flu pandemic and caused one of the deepest economic crises since the Great Depression of the 1930s.
Sukhun Lee   +3 more
doaj   +1 more source

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