Results 91 to 100 of about 8,284,419 (309)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Indian Journal of Ophthalmology, 2013 Background/Aim: The Andhra Pradesh Eye disease Study (APEDS) was a conventional cross-sectional study conducted in four locations during 1996-2000.
Srinivas Marmamula +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Retinal nerve fiber layer thickness in normal Egyptian population
Delta Journal of Ophthalmology, 2017 Purpose The aim of this study was to collect normative retinal nerve fiber layer thickness (RNFLT) data in the Egyptian population using the Spectralis SD-OCT and to assess its correlations with demographic data and ocular parameters.
Mohammad A.M. El-Hifnawy +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Age related histo-topography of portal vein in normal individuals and during portal hypertension
Кубанский научный медицинский вестник, 2016 General histological methods of studies of characteristics of different layers of portal vein in normal individuals and during portal hypertension syndrome in children and adults.
N. V. Getman
doaj
[Annual Summer Commencement North Texas State Normal College]
, 1921 The commencement program for the 1921 graduating class of North Texas State Normal College. The program is printed in black ink on a plain sheet of card stock. The cover reads, "Annual Summer Commencement. North Texas State Normal College. Denton, Texas.
North Texas State Normal College
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Wimb Lu, 2015 El tema de la locura ha estado presente a lo largo de la historia del ser humano; su concepto y definición han evolucionado de manera paralela a la evolución cultural y social que éste ha sufrido con el transcurrir de los siglos.
Mónica Cruz Alvarado
doaj