Results 71 to 80 of about 16,014,283 (355)
Responsibility in the age of precision genomics
Voices in Bioethics, 2017 What is normal, anyway? Genetically speaking, that’s precisely the question that the Obama administration’s Precision Medicine Initiative (PMI) seeks to answer.
Alexa Woodward
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
High-field MRI findings in epileptic dogs with a normal inter-ictal neurological examination
Frontiers in Veterinary ScienceIntroductionEpilepsy is one of the most common chronic neurological conditions affecting dogs. Previous research exploring the likelihood of a structural cause of epilepsy specifically in dogs with a normal inter-ictal examination is limited to a small ...
Stephanie Phillipps, Rita Goncalves
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Journal of Childhood, Education & Society, 2020 In this paper, we aim to better understand and trouble the discursive (re)production of what is taken as the ‘normal’ in ‘inclusive’ early childhood classrooms.
Karen Watson +2 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Assuming an inadequate posture: is it a bad costume or part of the normal development? [PDF]
Revista Ciencias de la Salud, 2003 Children adopt different postures as a normal consequence oftheir development, sometimes these attitudes are erroneouslycalled postural vicious. This article summarizes the childrenpostural development, explains why most of the positionsadopted by ...
Juan Carlos Rodríguez
doaj
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Normalizers and self-normalizing subgroups II
Open Mathematics, 2011 Abstract Let $\mathbb{K}$ be a field, G a reductive algebraic $\mathbb{K}$-group, and G 1 ≤ G a reductive subgroup. For G 1 ≤ G, the corresponding groups of $\mathbb{K}$-points, we study the normalizer N = N G(G 1).
openaire +4 more sources