Results 81 to 90 of about 16,014,283 (355)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Changing trends in the prevalence of visual impairment, uncorrected refractive errors and use of spectacles in Mahbubnagar district in South India

Indian Journal of Ophthalmology, 2013
Background/Aim: The Andhra Pradesh Eye disease Study (APEDS) was a conventional cross-sectional study conducted in four locations during 1996-2000.
Srinivas Marmamula, Jill E Keeffe, Saggam Narsaiah, Rohit C Khanna, Gullapalli N Rao   +4 more
doaj   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Ensemble 3D CNN and U-Net-based brain tumour classification with MKKMC segmentation

Automatika
Advanced brain cancer is the deadliest type with just a few months survival rate. Existing technologies hinder the objective of forecasting cancer.   This work aims to fulfil the pressing requirement for timely and precise identification of advanced ...
Arul Venkatachalam, Santhi Palanisamy, Poongodi Chinnasamy   +2 more
doaj   +1 more source

Retinal nerve fiber layer thickness in normal Egyptian population

Delta Journal of Ophthalmology, 2017
Purpose The aim of this study was to collect normative retinal nerve fiber layer thickness (RNFLT) data in the Egyptian population using the Spectralis SD-OCT and to assess its correlations with demographic data and ocular parameters.
Mohammad A.M. El-Hifnawy, Amir A Abo-Samra, Mohsen A Abou Shousha, Ehab M Kassem   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Georges Canguilhem et la question de la « subjectivité » vitale [PDF]

Meta: Research in Hermeneutics, Phenomenology and Practical Philosophy, 2014
This paper outlines a hypothesis regarding the close connection between two problems in Georges Canguilhem’s work. The first problem is that of Canguilhem’s insistence to include considerations about natural selection in his work and of the role that ...
Ciprian Jeler
doaj  

Bridgewater State Normal School. Massachusetts. 1925 [Catalogue] [PDF]

, 1923
https://vc.bridgew.edu/bns_catalogs/1085/thumbnail ...
Bridgewater State Normal School
core   +5 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source