Results 91 to 100 of about 3,407,167 (298)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Empirical Saddlepoint Approximation for GMM Estimators [PDF]

open access: yes
The empirical saddlepoint distribution provides an approximation to the sampling distributions for the GMM parameter estimates and the statistics that test the overidentifying restrictions.
Sowell, Fallaw
core  

Nearest normal approximation for certain operators

open access: yes, 1977
In this paper we show that binormal operators have nearest normal approximants. In fact, we exhibit nearest normals to such operators and, as a corollary, show that the hermitian part of a binormal operator with real spectrum is a nearest normal.
John Phillips
core   +1 more source

Cram\'er-type moderate deviation of normal approximation for unbounded exchangeable pairs [PDF]

open access: yes, 2022
In Stein's method, the exchangeable pair approach is commonly used to estimate the approximation errors in normal approximation. In this paper, we establish a Cram\'er-type moderate deviation theorem of normal approximation for unbounded exchangeable ...
Zhang, Zhuo-Song
core  

A New One-term Approximation to the Standard Normal Distribution

open access: yes, 2021
This paper deals with a new, simple one-term approximation to the cumulative distribution function (c.d.f) of the standard normal distribution which does not have closed form representation.
Hanandeh, Ahmad   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Piecewise log-normal approximation of size distributions for aerosol modelling [PDF]

open access: yesAtmospheric Chemistry and Physics, 2006
An efficient and accurate method for the representation of particle size distributions in atmospheric models is proposed. The method can be applied, but is not necessarily restricted, to aerosol mass and number size distributions.
K. von Salzen
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Approximate skew normal distribution

open access: yesJournal of Advanced Research, 2010
We propose a new approximate skew normal distribution, it is easy to calculate, convenient, mathematically tractable and is in a closed form. It is particularly useful when the probability density function occurs in an expression to be used for further ...
Samir K. Ashour, Mahmood A. Abdel-hameed
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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