Results 71 to 80 of about 3,407,167 (298)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The limits of normal approximation for adult height - old version
, 2020 Supplementary tables from the article "The limits of normal approximation for adult height"
Aulchenko Yurii +6 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Large deviations for weighted random sums
Nonlinear Analysis, 2013 In the present paper we consider weighted random sums ZN = ∑j=1 N ajXj, where 0 0. Throughout this paper N is independent of {X, Xj , j = 1, 2,...} and, for definiteness, it is assumed Z0 = 0. The main idea of the paper is to present results on theorems
Aurelija Kasparavičiūtė +1 more
doaj
Inequalities for Conditioned Normal Approximations
The Annals of Probability, 1977 Let $X_n$ be a sequence of i.i.d. random variables with mean 0 and variance 1. Let $S_n^\ast = n^{-\frac{1}{2}} \sum^n_{\nu=1} X_\nu$. We investigate in this paper the convergence order in conditioned central limit theorems, that is, the convergence order of $\sup_{t\in\mathbb{R}}|P(S_n^\ast < t|B) - \phi(t)|$.
Landers, D., Rogge, L.
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Approximations to distribution of median in stratified samples
Lietuvos Matematikos Rinkinys, 2011 We consider an Edgeworth type approximation to the distribution function of sample median in the case of stratified samples drawn without replacement. We give explicit expression of this approximation, and also its empirical version based on bootstrap ...
Andrius Čiginas, Tomas Rudys
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source