Results 101 to 110 of about 1,713,760 (284)
Identity of Proofs Based on Normalization and Generality [PDF]
Bulletin of Symbolic Logic, 2003 AbstractSome thirty years ago, two proposals were made concerning criteria for identity of proofs. Prawitz proposed to analyze identity of proofs in terms of the equivalence relation based on reduction to normal formin natural deduction. Lambek worked on a normalization proposal analogous to Prawitz's, based on reduction to cut-free form in sequent ...
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Hidrocefalia de pressão normal: visão atual sobre a fisiopatologia, diagnóstico e tratamento
Brazilian Neurosurgery, 2012 A hidrocefalia de pressão normal (HPN), descrita em 1964 por Salomón Hakim, é uma doença insidiosa que acomete, sobretudo, idosos entre 60 e 80 anos e manifesta-se por meio da tríade clínica de distúrbios da marcha, demência e incontinência urinária ...
Renan Muralho Pereira +3 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PharmaceuticalsIn this innovative research, we aim to reveal pyrazole-based Schiff bases as new multi-target agents. In this context, we re-synthesized three sets of pyrazole-based Schiff bases, 5a–f, 6a–f, and 7a–f, to evaluate their biological applications.
Ahmed M. Naglah +6 more
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Volatile oil analysis of spruce galls caused by Sacchiphantes viridis Ratz.
Acta Societatis Botanicorum Poloniae, 2014 The results of the analysis of volatile oil obtained from galls caused by Sacchiphantes viridis are presented in this paper. It was found that galls contain more oil than normal shoots. The composition of the oil obtained from galls differs significantly
Alicja Miszta
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Revista Mexicana de Ciencias Pecuarias, 1979 La reproducción normal de un hato es una de las bases para mantener una economía adecuada en las exploraciones pecuarias, sin embargo; existen factores limitantes de la eficiencia reproductiva y ...
José Juan Hernández Ledezma +2 more
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