Results 81 to 90 of about 4,855,327 (290)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Developing design-basis PSD loads for spent nuclear fuel transport: Insights from cask test results

Nuclear Engineering and Technology
From 2020 to 2021, multimodal transportation tests were conducted in South Korea. Surrogate fuel assemblies were loaded into a full-sized transportation cask for road and sea transportation tests at Doosan Enerbility and along a South Korean seashore ...
Woo-seok Choi, JaeHoon Lim
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Proximity effects and Andreev reflection in mesoscopic SNS junction with perfect NS interfaces

, 1999
Low temperature transport measurements on superconducting film - normal metal wire - superconducting film (SNS) junctions fabricated on the basis of 6 nm thick superconducting polycrystalline PtSi films are reported.
A. E. Plotnikov, A. Kastalsky, B.J. van Wees, C. Nguyen, C.W.J. Beenakker, E. B. Olshanetsky, I.K. Marmorkos, J. C. Portal, J. Kutchinsky, K. Flensberg, K. Maex, K. Oto, K.K. Likharev, M. Octavio, M. R. Baklanov, P. Xiong, P.H.C. Magnee, R. A. Donaton, T. I. Baturina, T.M. Klapwijk, V.B. Geshkenbein, V.N. Petrashov, W.M. van Huffelen, Z. D. Kvon   +23 more
core   +1 more source

Nonlinear spatial normalization using basis functions [PDF]

Human Brain Mapping, 1999
We describe a comprehensive framework for performing rapid and automatic nonlabel-based nonlinear spatial normalizations. The approach adopted minimizes the residual squared difference between an image and a template of the same modality. In order to reduce the number of parameters to be fitted, the nonlinear warps are described by a linear combination
J, Ashburner, K J, Friston
openaire   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

NONLINEAR PERTURBATIONS OF POLYHEDRAL NORMAL CONE MAPPINGS AND AFFINE VARIATIONAL INEQUALITIES

Tạp chí Khoa học Đại học Đà Lạt, 2012
This paper establishes an upper estimate for the Frechet normal cone to the graph of the nonlinearly perturbed polyhedral normal cone mappings in finite dimensional spaces.
Nguyễn Thành Quí
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Segmented Regression Based on B-Splines with Solved Examples [PDF]

Statistika: Statistics and Economy Journal, 2015
The subject of the paper is segmented linear, quadratic, and cubic regression based on B-spline basis functions. In this article we expose the formulas for the computation of B-splines of order one, two, and three that is needed to construct linear ...
Miloš Kaňka
doaj  

Leptonic Invariants, Neutrino Mass-Ordering and the Octant of $\theta_{23}$

, 2017
We point out that leptonic weak-basis invariants are an important tool for the study of the properties of lepton flavour models. In particular, we show that appropriately chosen invariants can give a clear indication of whether a particular lepton ...
Branco, G. C., Rebelo, M. N., Silva-Marcos, J. I.   +2 more
core   +1 more source